ID B6HW23_PENRW Unreviewed; 1632 AA.
AC B6HW23;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Pc22g19550 protein {ECO:0000313|EMBL:CAP99243.1};
GN ORFNames=Pc22g19550 {ECO:0000313|EMBL:CAP99243.1}, PCH_Pc22g19550
GN {ECO:0000313|EMBL:CAP99243.1};
OS Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS 54-1255) (Penicillium chrysogenum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC Penicillium chrysogenum species complex.
OX NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP99243.1, ECO:0000313|Proteomes:UP000000724};
RN [1] {ECO:0000313|EMBL:CAP99243.1, ECO:0000313|Proteomes:UP000000724}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC {ECO:0000313|Proteomes:UP000000724};
RX PubMed=18820685; DOI=10.1038/nbt.1498;
RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA Bovenberg R.A.L.;
RT "Genome sequencing and analysis of the filamentous fungus Penicillium
RT chrysogenum.";
RL Nat. Biotechnol. 26:1161-1168(2008).
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DR EMBL; AM920437; CAP99243.1; -; Genomic_DNA.
DR RefSeq; XP_002565858.1; XM_002565812.1.
DR STRING; 500485.B6HW23; -.
DR GeneID; 8315958; -.
DR KEGG; pcs:Pc22g19550; -.
DR VEuPathDB; FungiDB:PCH_Pc22g19550; -.
DR eggNOG; KOG4177; Eukaryota.
DR HOGENOM; CLU_000288_34_8_1; -.
DR OMA; MFLWIKM; -.
DR OrthoDB; 2330391at2759; -.
DR BioCyc; PCHR:PC22G19550-MONOMER; -.
DR Proteomes; UP000000724; Contig Pc00c22.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.1020; Prion-inhibition and propagation, HeLo domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR029498; HeLo_dom.
DR InterPro; IPR038305; HeLo_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23206:SF7; ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1; 1.
DR PANTHER; PTHR23206; MASK PROTEIN; 1.
DR Pfam; PF00023; Ank; 3.
DR Pfam; PF12796; Ank_2; 6.
DR Pfam; PF14479; HeLo; 1.
DR Pfam; PF05729; NACHT; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 21.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 16.
DR PROSITE; PS50088; ANK_REPEAT; 19.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 6..161
FT /note="Prion-inhibition and propagation HeLo"
FT /evidence="ECO:0000259|Pfam:PF14479"
FT DOMAIN 256..413
FT /note="NACHT"
FT /evidence="ECO:0000259|Pfam:PF05729"
FT REPEAT 795..827
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 828..860
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 861..893
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 893..925
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 926..954
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 959..991
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 992..1024
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1025..1057
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1058..1090
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1091..1118
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1124..1156
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1157..1189
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1190..1222
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1223..1255
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1256..1288
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1289..1321
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1322..1354
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1355..1387
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1388..1420
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 721..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1632 AA; 180679 MW; 64954E8DF9F5255C CRC64;
MEPVSFAIGI IGLAGLFSTC LDAVERFDSW KDYDFEFRAL VAQFKAQKIR LARWGLAVGL
EDDELSYDHN VLLDDPKIGS TIKEVLFAIN AVCRDEDKAF LTPMLGADEK SNNDQLFHRH
PPRESKRQKI GWVLRTKAKR VAQVDHFSKL VETLHNLIPI EDLKGYKGRK PTGAYGDSDG
RLSPPQFPFI FPSSRFMVLD EYRRDLHAWL LGSTSTNDLY EIFTERKIEG TCEWVLHQPW
FLEWTSPDFP DGCAKVLWIN GHAGSGKSVI CARVIENVSS NSKGPIAYFF FSSDFESRRD
PFIAIRIWLS QLLCHPVFFS LARERLTMQQ GQRATRGDTL KLLRDLVIKV PHCTFILDGL
DECRWVEQDH NSNDGASIVD FLEALQRAIY GTSTRILVVS RDEPEIRACL VNKSSTNDTI
IIQHSITPED VRFDLDMFSR SIVNKKLSTM TEATKSDISQ KLAERCNGQF LWVQMQESQL
RDWKSPKQLE KAINSTPPGL SKTYDREWMG ISLLSDDNRE RTISLLRWAA FALRPLSVSE
IAGALSISAN CDEVRIDEVP DRINDSYIET EIMRLGGSLI DIRNPMAGYD PRSRTVHLAH
FTVKEYLLCN LPAPGRLLQF NSSLKSSTEG IENLLAAKMC LCYVDCEGVW QETSEEGRDE
VLESFRNYAS RSWYQHASLG NMRDSDLVKS LNQLFDVENP NWASWKEWLD SRDESQRITC
VDSGEDSDSS TADDEQEIGP SNCADNSDLS VFKDGQPAQT LSMSPLYYAA WLGLTDTMDL
LLRSNKYSIN EQGKFGRTPL VAACERGNLE AVVKLLDSGA DLEIAGDNEH TPLQAAACNG
HAEVVKLLLE KGLNTHNGSD GSKTPLYCAC SNGHHQVVQM LLQREPDMID RQDRWIPLVA
ASDGGFLGIV QLLIQKGANV NVPTGSGRTP LYCACNAGHS EVMRLLLDEG AEIEYCCQDE
WTAVNVASYR GFLDIVLLLI ERGADINVQN EYGNTPLYNS CCTGHIEVVR QLLDKGADIN
RSNTFKWAPM NMASDQGLLD IVRLLIERGA DINVQDEFGR TPLSCACYRG HVEVVKTLVL
SGADLETANQ DGFTPLNVAS ERGFLDIVTI LVNKGVSLGS GAPDGWTSLH LASWDGYVDI
VTLLLEKGAA IDSAKSDGWT SLHVASERGY VDIVTLLLEK GAAIDSATPD GWTPLHLASW
DGSVDIVTLL LEKGAAIDSA TSDGWTSLHV ASGKGYVDIV TLLLEKGAGI DSATPDGMTP
LHLASENGYV DIVTLLLEKG AGIDSATPDG RTSLHLASWH GSVDVATLLL ERGADIASVD
KDGFTSLHFA VLGNSIEAVT LLLDKGAVLN SVANGGVVPL HLASLNDSPD VVNLLLDKEA
DIDSVEFYMG TPLRIASVSG HLDVVNLRLE RGAAIESGNF DDRRLLRYIP PHDQLEVITN
FLRSTKFKID IRVERGCAPL FYVIARGPSR AVQLLLPRLP ANAKDRYSAM PLPAAMRKGH
EEAIDKLTTL AGRQSNLDGL GRDLIWWVIG TGRGRVLDMV RQEYTQKFGT RITQGSNDKP
WSFVDLDQSQ SCDVCTLPIP TDTPYRRCED CNNFNICSQC VGVKVECLDT AHEWSSREPD
GFDNDVKGQK DG
//
