ID B6IT04_RHOCS Unreviewed; 361 AA.
AC B6IT04;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Chalcone synthase, putative {ECO:0000313|EMBL:ACI98675.1};
DE EC=2.3.1.74 {ECO:0000313|EMBL:ACI98675.1};
GN Name=bcsA {ECO:0000313|EMBL:ACI98675.1};
GN OrderedLocusNames=RC1_1268 {ECO:0000313|EMBL:ACI98675.1};
OS Rhodospirillum centenum (strain ATCC 51521 / SW).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Rhodospirillum.
OX NCBI_TaxID=414684 {ECO:0000313|EMBL:ACI98675.1, ECO:0000313|Proteomes:UP000001591};
RN [1] {ECO:0000313|Proteomes:UP000001591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51521 / SW {ECO:0000313|Proteomes:UP000001591};
RA Touchman J.W., Bauer C., Blankenship R.E.;
RT "Genome sequence of Rhodospirillum centenum.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACI98675.1, ECO:0000313|Proteomes:UP000001591}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51521 / SW {ECO:0000313|Proteomes:UP000001591};
RX PubMed=20500872; DOI=10.1186/1471-2164-11-325;
RA Lu Y.K., Marden J., Han M., Swingley W.D., Mastrian S.D., Chowdhury S.R.,
RA Hao J., Helmy T., Kim S., Kurdoglu A.A., Matthies H.J., Rollo D.,
RA Stothard P., Blankenship R.E., Bauer C.E., Touchman J.W.;
RT "Metabolic flexibility revealed in the genome of the cyst-forming alpha-1
RT proteobacterium Rhodospirillum centenum.";
RL BMC Genomics 11:325-325(2010).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; CP000613; ACI98675.1; -; Genomic_DNA.
DR RefSeq; WP_012566462.1; NC_011420.2.
DR AlphaFoldDB; B6IT04; -.
DR STRING; 414684.RC1_1268; -.
DR KEGG; rce:RC1_1268; -.
DR eggNOG; COG3424; Bacteria.
DR HOGENOM; CLU_034992_0_1_5; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000001591; Chromosome.
DR GO; GO:0102128; F:chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016210; F:naringenin-chalcone synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:ACI98675.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001591};
KW Transferase {ECO:0000313|EMBL:ACI98675.1}.
FT DOMAIN 70..205
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 232..333
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 142
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 361 AA; 38464 MW; DB828E79C5365298 CRC64;
MQPHAKILAV ATATPPHRFP QELTRDTARE VFAGRLRDFD RLSPVFTNAG IEARHSCVPI
DWYKKPRGWT DRNAVYLESA VAVLETATRT ALERAGLDTG AVDAIVAVSS TGIATPSLDA
LLMQRLGLRP DVQRLPVFGL GCAGGVLGLA RAANWAASMP DRTVLFLVVE LCGLSFRHGD
LSKANVVATA LFGDGAAAVL LRADPPEAGG RPTRGRSSGD LGRVVGWAEH TWPDTLDIMG
WRVEDDGLGV IFSQSIPRLV RERFGPVVDS FLDRQGLSRR RLAGSLCHPG GAKVLEALEE
VLAPATGGLD DARSVLRDYG NMSAATVLFV LERRIAGGAR GPHLMTALGP GFTAALALLE
L
//
