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Database: UniProt
Entry: B6JYJ2_SCHJY
LinkDB: B6JYJ2_SCHJY
Original site: B6JYJ2_SCHJY 
ID   B6JYJ2_SCHJY            Unreviewed;      1356 AA.
AC   B6JYJ2;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   26-FEB-2020, entry version 65.
DE   SubName: Full=ATP-dependent DNA helicase Hrp3 {ECO:0000313|EMBL:EEB06610.1};
GN   ORFNames=SJAG_01653 {ECO:0000313|EMBL:EEB06610.1};
OS   Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB06610.1, ECO:0000313|Proteomes:UP000001744};
RN   [1] {ECO:0000313|EMBL:EEB06610.1, ECO:0000313|Proteomes:UP000001744}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|SAAS:SAAS00539527}.
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DR   EMBL; KE651168; EEB06610.1; -; Genomic_DNA.
DR   RefSeq; XP_002172903.1; XM_002172867.2.
DR   STRING; 4897.EEB06610; -.
DR   EnsemblFungi; EEB06610; EEB06610; SJAG_01653.
DR   GeneID; 7052343; -.
DR   EuPathDB; FungiDB:SJAG_01653; -.
DR   eggNOG; ENOG410IREB; Eukaryota.
DR   eggNOG; ENOG410XNUT; LUCA.
DR   HOGENOM; CLU_000315_29_2_1; -.
DR   OMA; NIWKDDD; -.
DR   OrthoDB; 57339at2759; -.
DR   Proteomes; UP000001744; Unassembled WGS sequence.
DR   GO; GO:0031934; C:mating-type region heterochromatin; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0070615; F:nucleosome-dependent ATPase activity; IEA:EnsemblFungi.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:EnsemblFungi.
DR   GO; GO:0030466; P:chromatin silencing at silent mating-type cassette; IEA:EnsemblFungi.
DR   GO; GO:0060303; P:regulation of nucleosome density; IEA:EnsemblFungi.
DR   Gene3D; 3.40.50.10810; -; 1.
DR   InterPro; IPR041150; Cdh1_DBD.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR   InterPro; IPR023780; Chromo_domain.
DR   InterPro; IPR025260; DUF4208.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR000330; SNF2_N.
DR   Pfam; PF18196; Cdh1_DBD_1; 1.
DR   Pfam; PF00385; Chromo; 2.
DR   Pfam; PF13907; DUF4208; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2_N; 1.
DR   SMART; SM00298; CHROMO; 2.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01176; DUF4208; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF54160; SSF54160; 2.
DR   PROSITE; PS50013; CHROMO_2; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000313|EMBL:EEB06610.1};
KW   Helicase {ECO:0000313|EMBL:EEB06610.1};
KW   Hydrolase {ECO:0000313|EMBL:EEB06610.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:EEB06610.1};
KW   Nucleus {ECO:0000256|SAAS:SAAS00421658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001744}.
FT   DOMAIN          179..257
FT                   /note="Chromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50013"
FT   DOMAIN          285..346
FT                   /note="Chromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50013"
FT   DOMAIN          384..554
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          691..849
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          937..966
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1187..1266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..24
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..61
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..84
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1208..1222
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1223..1250
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1356 AA;  156535 MW;  F6F18C721B86CECC CRC64;
     MSSEALTATS QVQNLHNSIL PMNESVASMD DASDDLSEDA HSVRRKPHDP EYLDPELYGL
     RRSGRTRSQP GAYVQSYSSD DDSDSVTNSS KRRRNRQSKK ATSYDYEEEE EPFSSGEEDS
     NSDASSYGGT PKKRKRNVEV SYRNDEIRFS SRNSGGINYN EDAYFEDLED EEEYESYEYV
     TEEVENAPAI DLVLDHRLKA GADGSDAKND FEFLIKWQDK SYLHCTWETR EDMSETKGVK
     KIDNYTKTNI ILDKEIRSDP TTTREDIEAM DIERERKKEA YEEHKSVDRI VAEDFDENRN
     RIFLVKWKQL FYDACTWETE ELISRVAQDE IEEYQKRVNS ALSPARGTNY GNSRPTYRKL
     EQQPSYISGG ELRDFQLTGV NWMAYLWHKN ENGILADEMG LGKTVQTVAF LSYLAHSLRQ
     HGPFLVVVPL STVPAWQETL AAWAPDMNCI SYLGNAKSRQ MIQEHEFYDE RTQKLKFNVL
     LTTYEYVLKD RASLNNIKWQ YMAIDEAHRL KNSESSLYET LSQFKNANRL LITGTPLQNN
     IKELAALVDF LMPGKFQIRE EINFEAPDEE QESYIRNLQQ HLQPYILRRL KKDVEKSLPS
     KSERILRVEL SDSQTYWYKN ILTRNYRVLS QSTSNGSQLS LLNIVMELKK ASNHPYLFPG
     VEETWLKKTG GEGKREELLK GLIMNSGKMV LLDKLLTRLH RDGHRVLIFS QMVRMLDILG
     DYMSLRGYPF QRLDGTVPAA TRRISIDHFN APNSPDFVFL LSTRAGGLGI NLMTADTVII
     FDSDWNPQAD LQAMARAHRI GQKNHVMVYR FLSKDTIEED VLERARRKMI LEYAIISLGV
     TDKRKNSKSD KFSAEELSAI LKFGASNMFK NNDNQKKLED LNLDEILEHA EDHDTSNDVG
     GASMGGEEFL KQFEVTDYKA NVSWDDIIPA EERAKIEEEE RQQQEEERRK QEAELSSRRE
     RTSTLDLRED KTIEKISKPS RKRLIKDELL MEKEIRMLYR AMIKYGRIED RYDEIVKDAD
     LTTQDANVIK KISADLEASC KKAIAESESS SGEKNGKPAR KAILISFKGV KNINAETLIQ
     RLRDLEFLYQ AVDLNNLSSF RIKAPLRAVH GWSCKWSEVE DSMLLAGICK YGFGSWQSIR
     NDPELGLKDK LFLDDVKSQD SNEKHAPSAV HLVRRGEYLL TAFRESQQIA NDRPKMPHNR
     RQTSRSNLHR QLNRSEGSSR SPSVDSRADR RTSVASSRHN TPEHDTKTND STRSSNAPDH
     LDQRTRLRCK QLMHPVRKYL KSLKRDSRNL ERGQLVKLLA DCLTSIGKHI DKLVADTPTD
     KREGMTHDLW KFVCYFWPKE DVGHKNLISM YKKMGK
//
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