ID   B6JZC7_SCHJY            Unreviewed;       669 AA.
AC   B6JZC7;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=Anaphase-promoting complex subunit Apc3 {ECO:0000313|EMBL:EEB06895.1};
GN   Name=nuc2 {ECO:0000313|JaponicusDB:SJAG_01956};
GN   ORFNames=SJAG_01956 {ECO:0000313|EMBL:EEB06895.1};
OS   Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB06895.1, ECO:0000313|Proteomes:UP000001744};
RN   [1] {ECO:0000313|EMBL:EEB06895.1, ECO:0000313|Proteomes:UP000001744}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
CC   -!- SIMILARITY: Belongs to the APC3/CDC27 family.
CC       {ECO:0000256|ARBA:ARBA00038210}.
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DR   EMBL; KE651168; EEB06895.1; -; Genomic_DNA.
DR   RefSeq; XP_002173188.1; XM_002173152.2.
DR   AlphaFoldDB; B6JZC7; -.
DR   STRING; 402676.B6JZC7; -.
DR   EnsemblFungi; EEB06895; EEB06895; SJAG_01956.
DR   GeneID; 7049951; -.
DR   JaponicusDB; SJAG_01956; nuc2.
DR   VEuPathDB; FungiDB:SJAG_01956; -.
DR   eggNOG; KOG1126; Eukaryota.
DR   HOGENOM; CLU_008850_0_1_1; -.
DR   OMA; CEAWCVA; -.
DR   OrthoDB; 152021at2759; -.
DR   Proteomes; UP000001744; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR   GO; GO:0051728; P:cell cycle switching, mitotic to meiotic cell cycle; IEA:EnsemblFungi.
DR   GO; GO:0051301; P:cell division; IBA:GO_Central.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IBA:GO_Central.
DR   GO; GO:0000070; P:mitotic sister chromatid segregation; IEA:EnsemblFungi.
DR   GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR001440; TPR_1.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR   PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR   Pfam; PF12895; ANAPC3; 1.
DR   Pfam; PF00515; TPR_1; 1.
DR   Pfam; PF13174; TPR_6; 1.
DR   Pfam; PF13181; TPR_8; 2.
DR   SMART; SM00028; TPR; 9.
DR   SUPFAM; SSF48452; TPR-like; 3.
DR   PROSITE; PS50005; TPR; 5.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001744};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          115..148
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          367..400
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          469..502
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          503..536
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          537..570
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   669 AA;  75850 MW;  72AF13934C6EC5AF CRC64;
     MSERLRSIIW YSIDIQDYKN AIFFAERLYT MEGSLDNLCL LAHTHLLQLN YAMTFQLLEK
     HAINPISCYT FAKACLYLGK YKQGISALEM TQESWRRLPP QLGDSTVRRT RPDAGSMFEL
     LGHLYMKSGI VKKAAECFAE ALSANPYLFT AFQSLVAIGV HISVEEIFTN MPAFSIQEYS
     PSETTTPTPL FGKVPSAANT PTNPTSSYVP NIFAVGKGFE YLQTPQNNSL NTDPSNKFST
     PVPSFSAALK QTPLSRAGTN VTPNDASRFD TGTRKTPALF QDLRKTVIPP RPVSTATLTA
     PASSTSAAVV TSKKAIRSEQ AARPTDEEYI ITILKLIAQG CYALAQYDLP EALKCFQALP
     LAEQNSSFIL AKLGLVYFEL VQYDKAVFYF EKLRRGYPAR IEDMEVYSTA LWHLQKKVEL
     SYLAHEALEL HPYAPQSWCI LANCFSLQRE HSQALKCITR AIQLDSTFEY AYTLQGHEYS
     ANEEYEKAKT SFRRAIRINI RHYNAWYGIG MVYLKTGRND QADFHFKKAA EINPHNSVLM
     TCIGMIYERM KKFTYALEYY RRACVLDEKS SLARFKKAKV LVSLREYSKA LEELEALKVL
     APDEANVHFL LGKLYKRMKK RSLAMRHLTI AWNLDGKANH IIKESIEHLD VPEENLLGET
     GEIYKNLDE
//