ID B6K0W2_SCHJY Unreviewed; 428 AA.
AC B6K0W2;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=DNA kinase/phosphatase Pnk1 {ECO:0000313|EMBL:EEB07583.1};
GN Name=pnk1 {ECO:0000313|JaponicusDB:SJAG_02680};
GN ORFNames=SJAG_02680 {ECO:0000313|EMBL:EEB07583.1};
OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB07583.1, ECO:0000313|Proteomes:UP000001744};
RN [1] {ECO:0000313|EMBL:EEB07583.1, ECO:0000313|Proteomes:UP000001744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE651166; EEB07583.1; -; Genomic_DNA.
DR RefSeq; XP_002173876.1; XM_002173840.2.
DR AlphaFoldDB; B6K0W2; -.
DR STRING; 402676.B6K0W2; -.
DR EnsemblFungi; EEB07583; EEB07583; SJAG_02680.
DR GeneID; 7051059; -.
DR JaponicusDB; SJAG_02680; pnk1.
DR VEuPathDB; FungiDB:SJAG_02680; -.
DR eggNOG; KOG2134; Eukaryota.
DR HOGENOM; CLU_014938_3_1_1; -.
DR OMA; AADWKWW; -.
DR OrthoDB; 5490169at2759; -.
DR Proteomes; UP000001744; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR GO; GO:0046404; F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0046403; F:polynucleotide 3'-phosphatase activity; IBA:GO_Central.
DR GO; GO:0006284; P:base-excision repair; IEA:EnsemblFungi.
DR GO; GO:0006281; P:DNA repair; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0000012; P:single strand break repair; IEA:EnsemblFungi.
DR CDD; cd01625; HAD_PNP; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006549; HAD-SF_hydro_IIIA.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013954; PNK3P.
DR InterPro; IPR006551; Polynucleotide_phosphatase.
DR NCBIfam; TIGR01664; DNA-3'-Pase; 1.
DR NCBIfam; TIGR01662; HAD-SF-IIIA; 1.
DR PANTHER; PTHR12083; BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE; 1.
DR PANTHER; PTHR12083:SF9; BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF08645; PNK3P; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EEB07583.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001744};
KW Transferase {ECO:0000313|EMBL:EEB07583.1}.
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 48639 MW; B5C8FF3CB3665A0D CRC64;
MGNSDKQTSE NKRKRKPSTS GNEKNCPKEI VNDAAGVKKT RGQSTLSHFV KSSQSSPAIT
NKPLAWELYP SLYVGRSPCF SPTDRIIAFD LDGTLIRPKS GRTFPKDEND WVWLYGDIVP
KRLREEHASG ASIVIFTNQN GIPRRPATAP LFRRKIELLT QALDIPILVY AAIQKDKYRK
PLTGMWEEMK NVWLSKIDKS QACYVGDAAG RSADHASTDW KFAENIGIQF YTPEQFFLHK
ETEPPNAGPF QPKDFLQTKC SNNKETDFQP LDKQEVVVFV GLPSCGKSTF FETQIASHSN
YIVVNQDTLK TKARCLKFAR EQLEQGHSIV VDATNPDEKT RKDWILLAKE KHLPIRCVLF
TTPESVAKHN NVFRAIHERK TKLLPDVAFA SYKSRYQEPT VKEGFQSITP VSFTCLPEKA
DKWVQWQL
//
