ID B6K1K6_SCHJY Unreviewed; 797 AA.
AC B6K1K6;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Tre1 family protein {ECO:0000313|EMBL:EEB07037.1};
GN Name=tre1 {ECO:0000313|JaponicusDB:SJAG_02117};
GN ORFNames=SJAG_02117 {ECO:0000313|EMBL:EEB07037.1};
OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB07037.1, ECO:0000313|Proteomes:UP000001744};
RN [1] {ECO:0000313|EMBL:EEB07037.1, ECO:0000313|Proteomes:UP000001744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE651167; EEB07037.1; -; Genomic_DNA.
DR RefSeq; XP_002173330.1; XM_002173294.2.
DR AlphaFoldDB; B6K1K6; -.
DR STRING; 402676.B6K1K6; -.
DR EnsemblFungi; EEB07037; EEB07037; SJAG_02117.
DR GeneID; 7052050; -.
DR JaponicusDB; SJAG_02117; tre1.
DR VEuPathDB; FungiDB:SJAG_02117; -.
DR eggNOG; KOG2195; Eukaryota.
DR HOGENOM; CLU_005688_2_1_1; -.
DR OMA; QGSTEWV; -.
DR OrthoDB; 67337at2759; -.
DR Proteomes; UP000001744; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004180; F:carboxypeptidase activity; IBA:GO_Central.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001744};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 240..300
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 432..595
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 673..794
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 797 AA; 90740 MW; DF485DCF4F9F6EC8 CRC64;
MVVSNPEKSR NLYVPRPSPP PSYEEVEVEL LAEVPPVNST SLGTTPVHHF EVEEPPSPSR
LARYPRLQKK LEDLHEGWAS VRHSFNTRCL PLLRRIPFHL LYLFLVAIVL FITSYYGFSD
ETGVQIIQHY DEEYLVSYLL RTTNWRIGEY LPYFANKYRK MGTIGDNKLA EMMLYRLRYL
ALDNLDLNTF YTYAHFTKPP TLEVVDDSSF HALVSEIPIQ NSQQEYDAVI SYTYSADGNV
TAPLVYVNTG TDEDYSTLDD LNIQYKGAIV ILRATRDKVR QAVWTAERHG AVGCLVYDET
LSAGFASNAW YPTGPFAKPD TIFRTSLARS YYYMGDPLTP GFASTYRGKR LDRSTELVTS
KIPALPLSQQ NAQELMLRLV GRGHHIQTDA WKMSLPGVQN CWTGLGSNSE GEPLNVHIQT
NMNYEVDAQS INVLAEIEGM DRNEFIVVGA PRDSYDYDVL GTGLASASLM NLIEVFTEMR
SALSWRPRRT IVFASWDGRM YNALGSTEWL EQFEEELQGK IVAYVNVDVA FKGSRFTART
VPGLQKIVKR SFSIARRNFP SQDGYFMTDD FDIGPDYTSF LSHSGIPVIN IGFERDSKTE
PDPLLGSILD SKEWLTTYES GYEQYVNMLT EVWALILLSL SNDPIVPFSL ADEVDGYASF
INRLSATPAS QNIDFSSISE ELQALKLLAN NYTFFLEKWV KEEGHSMYLS TNRVYPELKN
VNQLLMSFER AFTDPVGLPG HEWYKHVIYG PNIRDQKPFV LPSVYEQLWI GNYTGAQQEL
DRVSRAIQRA TELFQFS
//
