ID B6K6X9_SCHJY Unreviewed; 658 AA.
AC B6K6X9;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 2.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Diacylglycerol binding protein Bzz1 {ECO:0000313|EMBL:EEB09283.2};
GN Name=bzz1 {ECO:0000313|JaponicusDB:SJAG_04479};
GN ORFNames=SJAG_04479 {ECO:0000313|EMBL:EEB09283.2};
OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=402676 {ECO:0000313|EMBL:EEB09283.2, ECO:0000313|Proteomes:UP000001744};
RN [1] {ECO:0000313|EMBL:EEB09283.2, ECO:0000313|Proteomes:UP000001744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=yFS275 / FY16936 {ECO:0000313|Proteomes:UP000001744};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE651168; EEB09283.2; -; Genomic_DNA.
DR RefSeq; XP_002175576.2; XM_002175540.2.
DR AlphaFoldDB; B6K6X9; -.
DR STRING; 402676.B6K6X9; -.
DR EnsemblFungi; EEB09283; EEB09283; SJAG_04479.
DR GeneID; 7051839; -.
DR JaponicusDB; SJAG_04479; bzz1.
DR VEuPathDB; FungiDB:SJAG_04479; -.
DR eggNOG; KOG3565; Eukaryota.
DR HOGENOM; CLU_015390_1_0_1; -.
DR OMA; TPMMEEP; -.
DR OrthoDB; 4260488at2759; -.
DR Proteomes; UP000001744; Unassembled WGS sequence.
DR GO; GO:0030479; C:actin cortical patch; IEA:EnsemblFungi.
DR GO; GO:0106006; F:cytoskeletal protein-membrane anchor activity; IEA:EnsemblFungi.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:EnsemblFungi.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:EnsemblFungi.
DR GO; GO:0030833; P:regulation of actin filament polymerization; IBA:GO_Central.
DR CDD; cd20824; C1_SpBZZ1-like; 1.
DR CDD; cd11912; SH3_Bzz1_1; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035459; Bzz1_SH3_1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR020454; DAG/PE-bd.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735:SF12; CDC42-INTERACTING PROTEIN 4, ISOFORM B; 1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00008; DAGPEDOMAIN.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00109; C1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PROSITE-
KW ProRule:PRU01077}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001744};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 6..272
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 398..448
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 535..595
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 600..658
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 471..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..487
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 73890 MW; 0FF607450CBD0116 CRC64;
MSVESVSISA YIKDDYKTVD SWVQNGVKWL EELHQFYKER SLIEKEYSQK LASLAKKYFE
KKNKRSSSLS IGDSPTSSAG SLECASLTTW TKILDGLTEE ARRIQNFSND LGSQISDQFL
NLQGQAESMR RNQHGYYNSL LDERERIDAG VKKAKQDYYS SCEVLESARQ KKDKLGDDKS
KRGYQDALTE MNNKKNGYVL TITEFNAHTK LYFSKLLPDV VDSLQQVNEF RVQKMNSLWK
HSLHLEKSCY SDLSQKTDEL NNEINLNSPN LDTVMFVKHN QKNWTPPNDL PFEPSPIWHD
TDSIATYDTN INYLRNMLIQ NRKDFETAAA SYESVMEESN KLEKAHSKSL LELPHAVVLK
MAEVEQLKAR FQTRMHDLQS RIDLILNTAG ALDEGTQPHD FRHTSFALPT NCDYCKSTIW
GLSKHGCVCK RCNYHCHARC EMKVPPECGK AEPLVSISRN ASLRRSNVGS ISSTNYANTT
RSVENHGAGS MRNEEVDDFG NIAVSRATTN TSESQPSPFG DSSQTPADAA ATSAAENETV
QVLYDYVGTT DDDLNVKEGQ MVVILQPDDG TGWVRARSGS AEGLVPASYL DLPGQASVAQ
DESYVRALYD YTAQTDLEIS LQAGDVIRVI QRDSGNGWSE GELDGRIGQF PANYVEDI
//
