ID B6K954_TOXGV Unreviewed; 1010 AA.
AC B6K954; A0A0F7VA95; B9Q9M5; S8GC14;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 81.
DE RecName: Full=AP-1 complex subunit gamma {ECO:0000256|PIRNR:PIRNR037094};
GN ORFNames=BN1205_098730 {ECO:0000313|EMBL:CEL77608.1}, TGVEG_313670
GN {ECO:0000313|EMBL:ESS35164.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS35164.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS35164.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS35164.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS35164.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS35164.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL77608.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL77608.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|PIRNR:PIRNR037094}.
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DR EMBL; LN714501; CEL77608.1; -; Genomic_DNA.
DR EMBL; AAYL02000039; ESS35164.1; -; Genomic_DNA.
DR AlphaFoldDB; B6K954; -.
DR STRING; 432359.B6K954; -.
DR PaxDb; 5811-TGME49_113670; -.
DR EnsemblProtists; ESS35164; ESS35164; TGVEG_313670.
DR VEuPathDB; ToxoDB:TGVEG_313670; -.
DR eggNOG; KOG1062; Eukaryota.
DR OMA; REPNTKK; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0030121; C:AP-1 adaptor complex; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 2.60.40.1230; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR017107; AP1_complex_gsu.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008153; GAE_dom.
DR PANTHER; PTHR22780; ADAPTIN, ALPHA/GAMMA/EPSILON; 1.
DR PANTHER; PTHR22780:SF5; AP-1 COMPLEX SUBUNIT GAMMA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR PIRSF; PIRSF037094; AP1_complex_gamma; 2.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR PROSITE; PS50180; GAE; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW ECO:0000256|PIRNR:PIRNR037094};
KW Golgi apparatus {ECO:0000256|PIRNR:PIRNR037094};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037094};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR037094};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037094}.
FT DOMAIN 871..1005
FT /note="GAE"
FT /evidence="ECO:0000259|PROSITE:PS50180"
FT REGION 662..709
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 725..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1010 AA; 107006 MW; 3D2447EDFB8D3460 CRC64;
MSCKLREFIR NIRAAKTAAD ERAVVSKECA EIRTAFKEGD GRYRHRNVAK VLFISMLGYP
TQFAQLECLK LLASPRFAEK RVGYLGLSCL LDEQSEVLML ATNSIKNDLQ HPNQYVNGLA
LTALGNIGTG EMCGAIMTQV EDLLRCSNPF IRKKAALCGV RVVKRVGDCE EKLLACLPAL
LADRNHGVLI SACALITALA ERDPSLVSTM RTHIPTLVKS LKACLTAGYA HAAEYDIAGI
TDPLLQCRLL RVLALLAKGD AESSASLSDV LAHVATNTEG AKNVGNSVLY ECVRTIMTIE
DDPGLRVLGV NILGRFLSSR ELNVKYVALG TLQQVVRVDS KAVMRHRDIL LDCLKDQDLS
LRRRAVEVLF CLITDDNVRG LVKELLNFLL MLNDAEFKQF VVNKIAVAAS RHAPSTRWQI
DTLLKLMTLG GDAVDDAITY SFVDLVVSTP PLHSYVVHKC YFSFQHSLSN NAALWQAGVY
CVGEFGDLLV KPEKGHLLSP NGGGSMTEDT LAITPRQVAD LLISVADQLS SFPKAKQGVL
TQTLLTAAAK LAARLPSQRE RLVGLLKRFE TSNNVEVQQR SSEYMGLLEW DEWKENTSIF
DRMPVCDAKL SSRRSLSSLG SGSFASLLSG RSGSAEALSP APASRPVGDV WFDATEVPLN
VGSPLAASSG RDDSEKDERN DRASQVSHGD SLFDEKPAQR NGIAAGSGKK TNDLLDLDDL
LNMGYSSESR ASPQGIPPHA SGAPSSGAGV AGGSAVGASS GDKSIDMLAD LLEGTSVSLG
GGAAVATPAG NSAADMRGST SAQGGGSLDS LFGLSPSQLS LPSGTSLSAV QSPTSADPFD
SFLASSAKGV NSGATPGIGS GLLGTVGSEN GAFPPMNVLN EDDLCVDFIC SRQGQSGSTA
TLLHEASGSE KGASIRAEFR NRGQAQITNL LFEAAVPKYL KLTIQPATGT SVPPTGTGVV
TQDMCVCFGD GASAPGAKPL LMKCRISFNK DGAMLQKFVN VGDFPAGLLA
//
