ID B6KTG1_TOXGV Unreviewed; 396 AA.
AC B6KTG1; A0A0F7UUZ7; A0A0N5E8G0; B9QGA6; S8GHC8;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=NOL1/NOP2/sun family domain-containing protein {ECO:0000313|EMBL:CEL72862.1};
DE SubName: Full=Putative ribosomal RNA small subunit methyltransferase B {ECO:0000313|EMBL:ESS30823.1};
DE EC=2.1.1.176 {ECO:0000313|EMBL:ESS30823.1};
GN ORFNames=BN1205_034250 {ECO:0000313|EMBL:CEL72862.1}, TGVEG_213970
GN {ECO:0000313|EMBL:ESS30823.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS30823.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS30823.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS30823.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS30823.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS30823.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL72862.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL72862.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01023}.
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DR EMBL; LN714494; CEL72862.1; -; Genomic_DNA.
DR EMBL; AAYL02000230; ESS30823.1; -; Genomic_DNA.
DR AlphaFoldDB; B6KTG1; -.
DR STRING; 432359.B6KTG1; -.
DR PaxDb; 5811-TGME49_013970; -.
DR EnsemblProtists; ESS30823; ESS30823; TGVEG_213970.
DR VEuPathDB; ToxoDB:TGVEG_213970; -.
DR eggNOG; KOG1122; Eukaryota.
DR OMA; PDAKWKL; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR InterPro; IPR023267; RCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22807:SF54; SAM_MT_RSMB_NOP DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01189; Methyltr_RsmB-F; 1.
DR PRINTS; PR02008; RCMTFAMILY.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU01023};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01023};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01023}.
FT DOMAIN 132..396
FT /note="SAM-dependent MTase RsmB/NOP-type"
FT /evidence="ECO:0000259|PROSITE:PS51686"
FT BINDING 246
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT BINDING 293
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ SEQUENCE 396 AA; 45253 MW; 66248E915575243D CRC64;
MNAFRLRHLE QALELYHKLP AATPSASTSP FPSLPLDLFV RHYFKCHKSI NSADKLFITS
HLYQIIKWKG LLDFLTPPPA AWSSRIRTYF ISDRWKLHST NQRLPPHLRC SFPEPLFARL
EAALGTVKAI QVCNILNEDP PTFLRVNSNK ITRERLYKFL VNKGVLVEKC ANSPFGLVLP
QRQKLGDLPE FKSGFFDIQD EASQLVAFKL QVEPGQKVLD YCAGSGGKTL AFGPLLGNTG
RLYLHDTREH MLLEAKKRLK RAGIPNYQLL FPHATPDHVF KKLRGQMDWV LCDVPCTATG
TLRRNPELKW KYSDDKLFDL VALQREIFAS ALIYMKPNKG RILYSTSSIL DEENVHQVKF
FCQQHGLVLS EAPFHALPQS KGMDGFFCAI LEKRRC
//
