ID B6Q3K1_TALMQ Unreviewed; 2140 AA.
AC B6Q3K1;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=SNF2 family helicase, putative {ECO:0000313|EMBL:EEA28090.1};
GN ORFNames=PMAA_029070 {ECO:0000313|EMBL:EEA28090.1};
OS Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS (Penicillium marneffei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA28090.1, ECO:0000313|Proteomes:UP000001294};
RN [1] {ECO:0000313|Proteomes:UP000001294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC {ECO:0000313|Proteomes:UP000001294};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS995899; EEA28090.1; -; Genomic_DNA.
DR RefSeq; XP_002144605.1; XM_002144569.1.
DR STRING; 441960.B6Q3K1; -.
DR VEuPathDB; FungiDB:PMAA_029070; -.
DR HOGENOM; CLU_000796_0_0_1; -.
DR OrthoDB; 103295at2759; -.
DR PhylomeDB; B6Q3K1; -.
DR Proteomes; UP000001294; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018117; C5_DNA_meth_AS.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR45626:SF26; FAMILY HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09120)-RELATED; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00094; C5_MTASE_1; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EEA28090.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1165..1552
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|SMART:SM00487"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1419..1465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1799..1846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1435..1455
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1822..1846
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2140 AA; 243007 MW; 8F53F3A21431F04A CRC64;
MSRPMTRGCA AKRKSSKTDI DNFDQEEQLN RASVDEVDQV VQQDDEVQLR ETRHEATPKT
NTNVNHRQVT RKRQKVEQSA PPTASEFVEI EYVSQLRHNF SPKKGLAGDL PPIHDLKQIF
EQITLHSIQE DGFKGFIQSL NGRQLRVATV CSGTESPILA LEMVVSELKK LNIPFSFKHL
FSAEIVEYKQ AYIERNFRPP LLFRDAIELH REFAYTAYGA KRKVPTRPDL LVAGFPCVDY
SNLNNWRKKF GERGESNDTL RGLLAYCEIH RPKIIILENI TNAPWAAIGR AFEKVGYCFR
HVKVDTKDFY LPQTRERGYA LCVEKSLVSN GDKMLNEWVS VFSGFGRRAS SPFTEFIDAD
DDVIEQRKLE RPPVAEPRSS PIWSLYKIRH ADVRRATTFG NGRPITHWEE GGKCCPATWM
DLPWFFSQVE RVWDTIDVNH LRTLAVGGYD NTYKIRCIDV SQGVDRDMDT KPFGIMGCIT
PCGMLYSTAR GGQVQGRELL SMQGLPLNRL SLTRESQSQM QDLAGNAMST TVVGPAIIAA
LTVCHSVLRV ENEEQQMIDI DDHIEESMPA VSLMSSYLTN MKTVASWDKT RVGWLPYIQA
SAGLTASLCS CEGPYGIGRY GLYRCMDCGF TACAACKVNP VHNYNSIPVS QLRARRDPKV
FREMLLYSLP ALIQPPPLPM NLYRTMLDQY STTPETTKIW KQYLETVTFV CQDTLMFKSI
KRRHIWTVVY EGANSTLQLT INAQGMHWKL FAKAPNDEPA RSYFREVVRH PIARMKVLQH
GSSLLDGEWQ ICGPLSRKDK TIYLQGTGDL LPSYENMCGL PDSAQKKVWS GILVGALDEA
IKGLSLDIRG YYERIPSCGG ALQSLHRRIS QETKKPDLFL FLDPRTLGPS QLDSWVFSTD
PRRKTDDSQR DILLQLDSKW SYQDLLHLGG STVLASHRKW IDVGIMSLVD RDSENGFASR
ILSSQITFQL NSQSCYDCYL PLLAACADVT GTPEEQHSWE VVETSNLQGM NEFAWTWARF
SAWSPCENWK PVDIDFEICG RCFPEQPKMA WAILRGKERP TEDPADAARC ERDYKLRPSP
FYLFGKLDSL KDGENKQRRH KCVALNVKTM FHRACGAIAH RQDDSTAVDF YWRIGSNDDT
DIPRPGSYRI LNNNGEPGAA QPPQFKILMR PDQLRSLRWV LSRESDQQVA FPEEEVEEAI
LAPLNWRAEA KVVVHRKIRG GILADHVGFG KTAVILGLID CQHEKDVLES EEPCNNGIPL
KATCIVVPDI LFDQWRGEIG RFLGEKYTVL EIDNILTLNS TPVKALKSAD IVLVSWTTFT
GALYFKRLEE VAGGPCPPKT NSSVRMFEAW SEDVLGSVET QVSALQNGGP EAFLSAIDRK
RSSIWGIDAY NRYLSSRKLA GKRGGKFKPD DDPLIAGQAA EDIPETSVPR LSEETAHGSC
KDTLPKEKAE SQNETNQKVL DRSAFGIPKT KQTSVEDVRN TVFHMYRFQR LVIDEFTYLN
QDRHALLASL KARSRWIMSG TPPIKGFASA ERMARLLNVY LGRPSDEDYE KSKYKRSFSD
QTETENFHFF REVPSRGWQF RRNGLAQHFC DVFMRQNTPD IPPIKWTVHY HPAVLSAVER
VLYLELKLFY ESYNPNTTGE KREKYSHDQR GRVSEIVDSC DSPEQSLIKR SSYYDDLPRW
STTDERIDTA LKFMKHRRRE AVKVLSELTI QAKAIAWLLH QLGQSDPRFD ALKASFDSND
CGDTDVSIKA HNLIDEALKS YQEGDWKQFW HSPNGRSVKI VSGMTDIDCD ETEEDEEIAD
EEEVARGDNV DANNEYVPLS QREKRTTQHK KTDLRPLPND KSEQEKELRE WTNRYRVNVL
ALVERIRALR FAESAYAFQD WSAIPDCQSC ERNNSRTRKE HNVLGKCGHI VCTSCLNNVL
SDNKCTVGDC RAAVDKQYVI PGSHFAMCRS INIPTPSGGT KVDALVGLLK DESLIPKEDQ
VILFLQFPDL EETVTAAFQL HNISYVSVGT TGRRGRNRIK TFAGHDKKVA ILHLGTENAA
GLNLQNANHV IFFAPFAAKS HYEYQSTITQ SSGRVIRFGQ KKEVHIWNLV TLNTLEVGIL
QGQDGRVLVR RASGEYELVL EDEVKVNDVK GFEVPVFDWK
//
