ID   B6QN70_TALMQ            Unreviewed;       891 AA.
AC   B6QN70;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=Carrier domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PMAA_061530 {ECO:0000313|EMBL:EEA22375.1};
OS   Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS   (Penicillium marneffei).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA22375.1, ECO:0000313|Proteomes:UP000001294};
RN   [1] {ECO:0000313|Proteomes:UP000001294}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC   {ECO:0000313|Proteomes:UP000001294};
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
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DR   EMBL; DS995903; EEA22375.1; -; Genomic_DNA.
DR   RefSeq; XP_002150984.1; XM_002150948.1.
DR   AlphaFoldDB; B6QN70; -.
DR   STRING; 441960.B6QN70; -.
DR   VEuPathDB; FungiDB:PMAA_061530; -.
DR   HOGENOM; CLU_008054_0_0_1; -.
DR   OrthoDB; 2230730at2759; -.
DR   PhylomeDB; B6QN70; -.
DR   Proteomes; UP000001294; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR013120; Far_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   PANTHER; PTHR45681:SF6; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45681; POLYKETIDE SYNTHASE 44-RELATED; 1.
DR   Pfam; PF18558; HTH_51; 1.
DR   Pfam; PF07993; NAD_binding_4; 1.
DR   Pfam; PF00550; PP-binding; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          112..152
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|Pfam:PF00550"
FT   DOMAIN          512..763
FT                   /note="Thioester reductase (TE)"
FT                   /evidence="ECO:0000259|Pfam:PF07993"
FT   REGION          49..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          84..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          171..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..209
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   891 AA;  99944 MW;  ECF0B912DD0F76FF CRC64;
     MIGACPSEKE WVSDVFVFDP VEGELVEVIL GIHYIRVARQ GLGKLLSRLT PSSKLPHPSP
     QPNAAETPKT NGVHEVRHAF DNMTTEPISE PHSNGANEKS KKELPELDIA GKVRDLICTL
     SGLEPDMIKP EADLANLGID SLMGMELARE IEIMFKSAFG FQVHPSAADR EADNHEKPHV
     NRFTHPKANG NMNGGSTKVN GTHSHANDPS MPNDMVVPTI AILDAFRETT QLTDQFIEQN
     NFGNYVQHTL PRLTKLCVIQ IIDGFEELGC SLRDAHLGQI LNRIKYLPKH EQFVTFFYGV
     LEKAGPVDLD GSRMTRTATA VPAESAYTLS QNLALDFPEH TYDSQLTYLT GSKLADYLTG
     KADGLQLIFA SAEGRNIVSG MYGKSPINMI DLVFGLLEGW WLFDDGRQHA LVPPSIWKTI
     MQSVGYGYVD WTYSNRPEAA IQRIIIALAS SKSRNRVHHP HQLLQRHSTD FTARQAIVDD
     FVKKYSSGFA APVVSKALEE GLEGHVDQCI LVTSATGSLG SHLVAYFTKL PNVKRMICVN
     RYSPSLDCRI RQRKALESKG LFLNSVELAK IHVLETDTVK PMMALSNLEY TKLINSVTHI
     IHNAWPMSIT RSIHTFEQQF KAMRNLIELA RQISCRYHHF HRNGPRVGFQ FISSIATVGC
     YPLFSGKARV PEDRMLVDSV MPTGYGEAKL IWETMLDETL HKYPQHFRPM IVRIGQIAGS
     EGSGYWNPVE HLAFLIKSSQ TLNILPDLEG DLSWCPVNVV AATLGELLLD EQTWYPVYHI
     ENPVRQPRRK MIHMLADDFH IPNTGIIPFK EWLERVRRSP SSPDDNPASN LAGFLDMYFV
     RMSCGGLILD TARSRENSWT LRDTGPVSRS LVMKFIQVWK ERGFLKQSVA S
//