ID B6QNS5_TALMQ Unreviewed; 440 AA.
AC B6QNS5;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein {ECO:0000256|RuleBase:RU369013};
GN ORFNames=PMAA_053670 {ECO:0000313|EMBL:EEA21563.1};
OS Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS (Penicillium marneffei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA21563.1, ECO:0000313|Proteomes:UP000001294};
RN [1] {ECO:0000313|Proteomes:UP000001294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC {ECO:0000313|Proteomes:UP000001294};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- FUNCTION: Plays a role in transport between endoplasmic reticulum and
CC Golgi. {ECO:0000256|RuleBase:RU369013}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|RuleBase:RU369013}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU369013}. Endoplasmic reticulum-Golgi
CC intermediate compartment membrane {ECO:0000256|RuleBase:RU369013};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU369013}. Golgi
CC apparatus membrane {ECO:0000256|RuleBase:RU369013}; Multi-pass membrane
CC protein {ECO:0000256|RuleBase:RU369013}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ERGIC family.
CC {ECO:0000256|RuleBase:RU369013}.
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DR EMBL; DS995903; EEA21563.1; -; Genomic_DNA.
DR RefSeq; XP_002150172.1; XM_002150136.1.
DR AlphaFoldDB; B6QNS5; -.
DR STRING; 441960.B6QNS5; -.
DR VEuPathDB; FungiDB:PMAA_053670; -.
DR HOGENOM; CLU_034705_1_0_1; -.
DR OrthoDB; 506854at2759; -.
DR PhylomeDB; B6QNS5; -.
DR Proteomes; UP000001294; Unassembled WGS sequence.
DR GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; IEA:UniProtKB-UniRule.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:UniProtKB-UniRule.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:UniProtKB-UniRule.
DR InterPro; IPR045888; Erv.
DR InterPro; IPR012936; Erv_C.
DR InterPro; IPR039542; Erv_N.
DR PANTHER; PTHR10984; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN; 1.
DR PANTHER; PTHR10984:SF25; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3; 1.
DR Pfam; PF07970; COPIIcoated_ERV; 1.
DR Pfam; PF13850; ERGIC_N; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|RuleBase:RU369013};
KW ER-Golgi transport {ECO:0000256|RuleBase:RU369013};
KW Golgi apparatus {ECO:0000256|RuleBase:RU369013};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369013};
KW Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369013};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369013}; Transport {ECO:0000256|RuleBase:RU369013}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369013"
FT TRANSMEM 403..425
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369013"
FT DOMAIN 8..97
FT /note="Endoplasmic reticulum vesicle transporter N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13850"
FT DOMAIN 143..422
FT /note="Endoplasmic reticulum vesicle transporter C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07970"
SQ SEQUENCE 440 AA; 49103 MW; 3BC417F10D6F3088 CRC64;
MPPKSRFTRL DAFAKTVEDA RVRTTSGGIV TLVSLVVILW LVWGEWADYR RVVVLPELIV
DKSRGERMEI HLNMTFPRLP CELLTLDVMD VSGEQQMGVV HGLNKVRLSS VADGGRVIDV
SKLELHSQNE VAIHLDPEYC GECGGASPPE NAKKPGCCNT CEEVREAYAL KSWAFGKGEN
IEQCQREGYA DRIDAQRREG CRIEGDIRVN KVIGNFHIAP GRSFSSGNMH VHDLDTYLDR
ELADYEKHTM SHIIHQLRFG PQLSDEVSQR WQWTDHHHTN PLDSTQQLTN EPAYNYNYYI
KVVSTSYLPL GWDSARSDQL HGDDQFTPLG LHGAAHGTAG SIETHQYSVT SHKRSLHGGN
DAAEGHQERI HAEGGIPGVF FNYDISPMKV VNREARAKTF TGFLTGVCAV IGGTLTVAAA
VDRFLYEGSR RIRKSAAHTE
//
