ID B6QRK0_TALMQ Unreviewed; 1275 AA.
AC B6QRK0;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Pre-mRNA splicing factor (Prp24), putative {ECO:0000313|EMBL:EEA20848.1};
GN ORFNames=PMAA_046670 {ECO:0000313|EMBL:EEA20848.1};
OS Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS (Penicillium marneffei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA20848.1, ECO:0000313|Proteomes:UP000001294};
RN [1] {ECO:0000313|Proteomes:UP000001294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC {ECO:0000313|Proteomes:UP000001294};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
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DR EMBL; DS995904; EEA20848.1; -; Genomic_DNA.
DR RefSeq; XP_002151848.1; XM_002151812.1.
DR AlphaFoldDB; B6QRK0; -.
DR STRING; 441960.B6QRK0; -.
DR VEuPathDB; FungiDB:PMAA_046670; -.
DR HOGENOM; CLU_003925_0_0_1; -.
DR OrthoDB; 3035286at2759; -.
DR PhylomeDB; B6QRK0; -.
DR Proteomes; UP000001294; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd12296; RRM1_Prp24; 1.
DR CDD; cd12299; RRM4_Prp24; 1.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR034397; Prp24_RRM1.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR031766; RRM_occluded.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR10352; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G; 1.
DR Pfam; PF00076; RRM_1; 3.
DR Pfam; PF16842; RRM_occluded; 1.
DR SMART; SM00386; HAT; 3.
DR SMART; SM00360; RRM; 4.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50102; RRM; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 832..916
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 907..984
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 998..1074
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 1112..1185
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1189..1275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..94
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..830
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1237..1263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1275 AA; 143134 MW; FE8F47F5FAAEA8B9 CRC64;
MDINSLLSPQ ESAAQSRQSN AQARSNKGNP STASGQTSNT SPQKPRRGRA AGSKYSTGPS
PVARQALKSR LPERANAPNP PQNSNSQGNP AGKGNGSMTA LAEAAALQGQ SQPQSQSHPS
HNQKGNQPVY SNMSISPIYP NPKPVKLVQN PPRAPEPREF VKRNFSQSSL HPEAQQQANQ
LFSHIQANPH SYESHVQFIQ LLHTGFVNHV YPPHDPDAHG DPRAYDLLKD LRSAREDMDK
LFAMGEDLWV EWIQDETMVA QTVDERIAVM ELCRRAVEEE YGSTKLWTMF GEWMLYLYNS
ANGQAGQNQW SEEDRLVGRE VFSWPSVFEI WQRAADATRW RIHDSHLVWS KFLELCIQDF
SHNQTNEKAS QVRATFESRL QTPHAAWDET FQIFSGFVSQ YFNANYEEIM ANAVARASDA
KAKYAARQDF EHKVQRALES KDRNLEWAVY SEYIEWELLQ DPRKNMYSPH LINALYQRAL
LRFPTDVPMW EDCVMFLIQP PVPVPRNEIA PVLPTIERAT RHCPWSGSLW SQCLLVAERE
GLSFDQIVEL KHRATSTGLL DAGGLEEVIK VHSMWCSYLR RRAFLPDATD EDLDVAEVGI
RSAIERVQEL GENKYGKSYQ GDPYFRLERI YTRYLSESGS WDSAREYYKG LIATRGNSYE
FWLDYYNWEI MSWRTFVEAA MTPEAARRTP GPSYATAVLK QAIRRPDLDW PEKVMTKYIA
HCEDYEDADE LQEALVETQM AMKAVARRRQ KEALERAAAQ QSAAASTEAA QVAAAESMGT
EGDVAAAAAA SKRKREEDSL ETTETPHKKA RPETISSDHK EPAELKRDRE HSTVMVKRMP
SDIIESQIRQ FFRDCGPIVD IKFLPSEHDL TTAVVEFETQ EDAAAALTRD QKRINGQTVD
VEMGSGSTVY VTNFPPTADE AFIRSLFSEA GEIVEVRFPS LKYNTHRRFC YVQFKSPDQA
IAATKLDNNV VGDGLNLQVK ISDPSARQDR QGPMYEEREI HISNIHFDAR ENDLKELFSK
YGTIETVRIP SKVNGEHRGF GFIVFSKKEE ATAALAMHKQ DFRGRPLQVK VSTPVPVKRA
ATIITPKARS ESAEPKGGDL ESQGAADDRA ARTLGLMNIP DTVNDSRIRA IAEPFGPLVK
IILRPDREGA IVEFVDIKAA GKASLELEGH EIAPGRLIRV GTANDVLKRN GPSVSGPAKP
KTTKTFMPQV GGPIKRPTQP GAGRRGGLGF KRGGSVASGR SDEHHEHHEK VEGATEQKPQ
KTNDDFRAMF SNGKQ
//
