ID B6QVT3_TALMQ Unreviewed; 1348 AA.
AC B6QVT3;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Oligomycin resistance ATP-dependent permease yor1, putative {ECO:0000313|EMBL:EEA19146.1};
GN ORFNames=PMAA_014070 {ECO:0000313|EMBL:EEA19146.1};
OS Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS (Penicillium marneffei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA19146.1, ECO:0000313|Proteomes:UP000001294};
RN [1] {ECO:0000313|Proteomes:UP000001294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC {ECO:0000313|Proteomes:UP000001294};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS995906; EEA19146.1; -; Genomic_DNA.
DR RefSeq; XP_002153531.1; XM_002153495.1.
DR VEuPathDB; FungiDB:PMAA_014070; -.
DR HOGENOM; CLU_000604_27_1_1; -.
DR OrthoDB; 3295317at2759; -.
DR PhylomeDB; B6QVT3; -.
DR Proteomes; UP000001294; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd18597; ABC_6TM_YOR1_D1_like; 1.
DR CDD; cd18606; ABC_6TM_YOR1_D2_like; 1.
DR CDD; cd03250; ABCC_MRP_domain1; 1.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF443; MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I; 1.
DR Pfam; PF00664; ABC_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..788
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 808..832
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 882..899
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 905..925
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 116..423
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 477..706
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 772..1048
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 1083..1334
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 467..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..497
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1348 AA; 150674 MW; 8276E7A944CC81CD CRC64;
MDTKKENIWR GRFNPLRWGK PPPIPGEREV TKEYKAGIWN QLTFGWMGDH MSTGYRRPLE
YNDIWLLHPD RTVEPLAIKL QTSFQERVSQ NQKNPLLWAI YDTFRYDILL SAINRMLADL
FVVFAPFTLR YLLIFVQDSY DARMDVSSSP FIGKGIGLVV GIIVMQVLQS LTNCHFQYRS
MLVGGQTRSV LISAIFTKSM KLSNRAKIQG TTVTLKKPSI NGKKKQAETF QQDAWTDGRI
VNLMSNDTQR IFQASKVFHY VWSSPISIIL AIILLVINLT YSALPGIAIL VIGLVGVTYV
VRTLSRRRDI INGITDQRIS LTQEILQSIR FVKYFAWEKS FQSRLTDIRA KEIHSIQILL
TIRSALGAVA MAIPIFANML AYITYSLTDH NLNAAVVFSS LALFNCLRTP LNWLPVAIGQ
AVDAWTSIQR IEAFLLAEEI QEQADLDREA PAAIQLNDAS FTWEKPIETK TVDDDDDDDE
DTNKHGEKSE SPHDERQPFQ LKSITMTAGR GELVAIVGAV GSGKTSLLSA IVGEMRKTSG
QIILGGSKAY CPQHAWIQNT TIRDNIIFGK PFDPEWYQRV VEACALVADF KILPAGDMTE
IGERGINLSG GQKQRINLAR AIYFQSDIIL MDDPLSAVDA HVGRHILENA ICGLLKGKSR
ILATHQLHVL SRCDRVIWLE NGQVITEGPY TELLERHEGF RTLVSQVSGG DQDNSQDENE
NHEDQPENES SGTATNDSSL KLVTAETKAV KSVPWSVYVT YARASGSVFN IIGIFVLLVT
FRGANIMTSL WLSYWSEDQF SLSRNQYIGI YAALAVLQGL LLFSFSAATS IFGTRASKKL
LEIATWKVLR TPVSFFDTTP LGRITRRFTK DIDWMDNNLT DALRMYLVVF SMIISTFVLT
IAYFYFFAIA IIPLACALLI WTAYYRASAR ELKRYESLLD SSMYARFTEA LTGVPCVRAY
ELQGQFTTRL ISAIEDMGSA QFLTFGNERW LSVRLDAIGN TLVLVTGILV LIDRYNISPS
ISGLILSYSL SLVQLIQLTV RQFSDVEAAM NGSERIIEYT SLPSEAQLDL NKTPPKWPEN
GQIQFENVGM RYRPGLPLAL SNFNLNITGG ERIGIVGRTG AGKSSILSTL FRMVELSSGK
ISIDGVDIST IGLHELRSKL AIIPQDPTLF KGTVRSNLDP FGDHSDLVLW NALRQSCLIP
LDPSSSDSDL DKADTSLPRS LNRVTLDSPV ADEGQNFSLG QRQLLALSRA LVRDSKIIVI
DEGTSSVDQD TDKQVQRTIQ HGFKGKTILS VAHRLHTVLN YDRICVMEKG EIVELGTPKA
LWQAGGIFSR MCQRSGIGNK DFEAKLYS
//
