ID B6QVV2_TALMQ Unreviewed; 72 AA.
AC B6QVV2;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=General transcription and DNA repair factor IIH subunit TFB5 {ECO:0000256|RuleBase:RU368032};
GN ORFNames=PMAA_014590 {ECO:0000313|EMBL:EEA19199.1};
OS Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OS (Penicillium marneffei).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441960 {ECO:0000313|EMBL:EEA19199.1, ECO:0000313|Proteomes:UP000001294};
RN [1] {ECO:0000313|Proteomes:UP000001294}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 18224 / CBS 334.59 / QM 7333
RC {ECO:0000313|Proteomes:UP000001294};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- FUNCTION: In NER, TFIIH acts by opening DNA around the lesion to allow
CC the excision of the damaged oligonucleotide and its replacement by a
CC new DNA fragment. In transcription, TFIIH has an essential role in
CC transcription initiation. When the pre-initiation complex (PIC) has
CC been established, TFIIH is required for promoter opening and promoter
CC escape. {ECO:0000256|RuleBase:RU368032}.
CC -!- SUBUNIT: Component of the 7-subunit TFIIH core complex.
CC {ECO:0000256|RuleBase:RU368032}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU368032}.
CC -!- SIMILARITY: Belongs to the TFB5 family. {ECO:0000256|ARBA:ARBA00007470,
CC ECO:0000256|RuleBase:RU368032}.
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DR EMBL; DS995906; EEA19199.1; -; Genomic_DNA.
DR RefSeq; XP_002153584.1; XM_002153548.1.
DR AlphaFoldDB; B6QVV2; -.
DR STRING; 441960.B6QVV2; -.
DR VEuPathDB; FungiDB:PMAA_014590; -.
DR HOGENOM; CLU_166246_3_1_1; -.
DR OrthoDB; 419at2759; -.
DR PhylomeDB; B6QVV2; -.
DR Proteomes; UP000001294; Unassembled WGS sequence.
DR GO; GO:0000439; C:transcription factor TFIIH core complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005675; C:transcription factor TFIIH holo complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.1220; TFB5-like; 1.
DR InterPro; IPR035935; TFB5-like_sf.
DR InterPro; IPR009400; TFIIH_TTDA/Tfb5.
DR PANTHER; PTHR28580; GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5; 1.
DR PANTHER; PTHR28580:SF1; GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5; 1.
DR Pfam; PF06331; Tfb5; 1.
DR SMART; SM01395; Tbf5; 1.
DR SUPFAM; SSF142897; TFB5-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU368032};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU368032};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU368032};
KW Reference proteome {ECO:0000313|Proteomes:UP000001294};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU368032};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU368032}.
SQ SEQUENCE 72 AA; 8379 MW; 5E46B8ABEEF6FBAC CRC64;
MPRAVKGVLV ECDPSVKAII LKYDEEKHDY IVEDLDDDRH LVIKESQLQN LKERLGQELD
QKVMQPEESD SE
//
