ID B6TXZ3_MAIZE Unreviewed; 443 AA.
AC B6TXZ3;
DT 16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT 16-DEC-2008, sequence version 1.
DT 24-JAN-2024, entry version 93.
DE RecName: Full=S-acyltransferase {ECO:0000256|RuleBase:RU079119};
DE EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119};
DE AltName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119};
GN Name=100284840 {ECO:0000313|EnsemblPlants:Zm00001eb317860_P001};
GN ORFNames=ZEAMMB73_Zm00001d021065 {ECO:0000313|EMBL:ONM56236.1};
OS Zea mays (Maize).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX NCBI_TaxID=4577 {ECO:0000313|EMBL:ACG41976.1};
RN [1] {ECO:0000313|EMBL:ACG41976.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18937034; DOI=10.1007/s11103-008-9415-4;
RA Alexandrov N.N., Brover V.V., Freidin S., Troukhan M.E., Tatarinova T.V.,
RA Zhang H., Swaller T.J., Lu Y.P., Bouck J., Flavell R.B., Feldmann K.A.;
RT "Insights into corn genes derived from large-scale cDNA sequencing.";
RL Plant Mol. Biol. 69:179-194(2009).
RN [2] {ECO:0000313|EMBL:ONM56236.1, ECO:0000313|Proteomes:UP000007305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb317860_P001,
RC ECO:0000313|Proteomes:UP000007305};
RC TISSUE=Seedling {ECO:0000313|EMBL:ONM56236.1};
RG Maize Genome Sequencing Project;
RA Ware D.;
RT "Update maize B73 reference genome by single molecule sequencing
RT technologies.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:Zm00001eb317860_P001}
RP IDENTIFICATION.
RC STRAIN=cv. B73 {ECO:0000313|EnsemblPlants:Zm00001eb317860_P001};
RG EnsemblPlants;
RL Submitted (MAY-2021) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-
CC hexadecanoyl-L-cysteinyl-[protein]; Xref=Rhea:RHEA:36683, Rhea:RHEA-
CC COMP:10131, Rhea:RHEA-COMP:11032, ChEBI:CHEBI:29950,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57379, ChEBI:CHEBI:74151;
CC EC=2.3.1.225; Evidence={ECO:0000256|RuleBase:RU079119};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- DOMAIN: The DHHC domain is required for palmitoyltransferase activity.
CC {ECO:0000256|RuleBase:RU079119}.
CC -!- SIMILARITY: Belongs to the DHHC palmitoyltransferase family.
CC {ECO:0000256|ARBA:ARBA00008574, ECO:0000256|RuleBase:RU079119}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EU969858; ACG41976.1; -; mRNA.
DR EMBL; CM007650; ONM56236.1; -; Genomic_DNA.
DR RefSeq; NP_001151207.1; NM_001157735.1.
DR AlphaFoldDB; B6TXZ3; -.
DR SMR; B6TXZ3; -.
DR IntAct; B6TXZ3; 5.
DR STRING; 4577.B6TXZ3; -.
DR PaxDb; 4577-GRMZM5G868588_P01; -.
DR EnsemblPlants; Zm00001eb317860_T001; Zm00001eb317860_P001; Zm00001eb317860.
DR GeneID; 100284840; -.
DR Gramene; Zm00001eb317860_T001; Zm00001eb317860_P001; Zm00001eb317860.
DR KEGG; zma:100284840; -.
DR eggNOG; KOG1311; Eukaryota.
DR HOGENOM; CLU_018741_2_2_1; -.
DR InParanoid; B6TXZ3; -.
DR OMA; GSNKFCL; -.
DR OrthoDB; 276762at2759; -.
DR Proteomes; UP000007305; Chromosome 7.
DR ExpressionAtlas; B6TXZ3; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019706; F:protein-cysteine S-palmitoyltransferase activity; IBA:GO_Central.
DR GO; GO:0006612; P:protein targeting to membrane; IBA:GO_Central.
DR InterPro; IPR001594; Palmitoyltrfase_DHHC.
DR PANTHER; PTHR22883:SF390; S-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22883; ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF01529; DHHC; 1.
DR PROSITE; PS50216; DHHC; 1.
PE 1: Evidence at protein level;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU079119}; Membrane {ECO:0000256|RuleBase:RU079119};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B6TXZ3};
KW Reference proteome {ECO:0000313|Proteomes:UP000007305};
KW Transferase {ECO:0000256|RuleBase:RU079119, ECO:0000313|EMBL:ACG41976.1};
KW Transmembrane {ECO:0000256|RuleBase:RU079119};
KW Transmembrane helix {ECO:0000256|RuleBase:RU079119}.
FT TRANSMEM 46..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT TRANSMEM 75..98
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT TRANSMEM 195..218
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT TRANSMEM 238..263
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU079119"
FT DOMAIN 151..275
FT /note="Palmitoyltransferase DHHC"
FT /evidence="ECO:0000259|Pfam:PF01529"
FT REGION 106..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 443 AA; 49840 MW; 7AD504012C9D89DC CRC64;
MYGPPSRGGG GAGTAGEQPR VYQVWRGSNE FFLQGRFIFG PDVRSLFLTI FLILAPMVVF
CIFVARHLIN DFPDHWGVSV MVIVIVFTVY DLTLLLLTSG RDPGIVPRNT HPPETDAIEM
NNDAGNGQTP QQLRLPRTKD VIVNGVIVKV KYCDTCMLYR PPRCSHCSIC NNCVERFDHH
CPWVGQCIGL RNYRFFYMFV FSTTLLCLYV FGFCWVYIIK IRDAEQSSIW KAMLKTPASI
VLIIYCFICV WFVGGLSVFH FYLMSTNQTT YENFRYRYDR RANPYNIGIL NNFMEIFCTA
VPPSKNNFRA RVPVEQGLQQ SRAPARGFMS LNMDKPVGDF ELSRKPVSWD EPRSAADIRD
LEVGLGGLLD EKEGRIAHAS PDLSRDALPE LVEGRAGMHS RRSSWGHRSG TSESVDSIAV
QMGTGDSHWG SISSAHGTTS GAH
//
