ID B6WBM6_9FIRM Unreviewed; 456 AA.
AC B6WBM6;
DT 20-JAN-2009, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=CBS domain-containing protein {ECO:0000259|PROSITE:PS51371};
GN ORFNames=ANHYDRO_02009 {ECO:0000313|EMBL:EEB35238.1};
OS Anaerococcus hydrogenalis DSM 7454.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Anaerococcus.
OX NCBI_TaxID=561177 {ECO:0000313|EMBL:EEB35238.1, ECO:0000313|Proteomes:UP000005451};
RN [1] {ECO:0000313|EMBL:EEB35238.1, ECO:0000313|Proteomes:UP000005451}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7454 {ECO:0000313|EMBL:EEB35238.1,
RC ECO:0000313|Proteomes:UP000005451};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEB35238.1, ECO:0000313|Proteomes:UP000005451}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7454 {ECO:0000313|EMBL:EEB35238.1,
RC ECO:0000313|Proteomes:UP000005451};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Anaerococcus hydrogenalis (DSM 7454).";
RL Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UPF0053 family.
CC {ECO:0000256|ARBA:ARBA00006337}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEB35238.1}.
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DR EMBL; ABXA01000047; EEB35238.1; -; Genomic_DNA.
DR RefSeq; WP_004815851.1; NZ_ABXA01000047.1.
DR AlphaFoldDB; B6WBM6; -.
DR STRING; 561177.ANHYDRO_02009; -.
DR eggNOG; COG1253; Bacteria.
DR Proteomes; UP000005451; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF33; UPF0053 PROTEIN YEGH; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 223..283
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 289..346
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 456 AA; 52621 MW; C1B482EAD4D058FF CRC64;
MDTEGPYWKL RIFLIVLALI FLNALINMIF SSLTSINHQK LRDMVENGDE KAKDVLKISQ
DQQRLMQSQN FQDAVLSIIT ITYLLLNIKD SLAIFLNRES DFMQLVIMVF MVVLFVVFKR
IFANMIPQRI GIRNPYTISK KTAGFAKFIL FLTKPFVNII NKVTNLIMNI FGIESKAIEK
EVTAEQIKSI VQVGEDQGVL RPLESKMINS IMDFDDVWAE EIMTARPEVF MIDIKDRDRK
YLDEFIKLKH SRIPVYDEEV DNILGIIYTK DYLLEALDVG IASVDIRKLI KPAFFVPEKI
ETDKLFSQMQ KDHTHMAILI DEYGGFSGLV TMEDLVEEIV GDMDDTFDKD LPDIRTSTKG
SYIVKGSTSI KDLNDILGLD IDEENDQYDT VGGFIIDKLG FIPDDDCDQT VIYKDYEFKI
LYIEETRIKI VRVKKINKSD QNLDENIKNK EKNTTN
//
