ID B6YTY8_THEON Unreviewed; 532 AA.
AC B6YTY8;
DT 20-JAN-2009, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Membrane bound hydrogenase, MbhH subunit {ECO:0000313|EMBL:ACJ17079.1};
GN OrderedLocusNames=TON_1589 {ECO:0000313|EMBL:ACJ17079.1};
OS Thermococcus onnurineus (strain NA1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=523850 {ECO:0000313|EMBL:ACJ17079.1, ECO:0000313|Proteomes:UP000002727};
RN [1] {ECO:0000313|EMBL:ACJ17079.1, ECO:0000313|Proteomes:UP000002727}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA1 {ECO:0000313|EMBL:ACJ17079.1,
RC ECO:0000313|Proteomes:UP000002727};
RX PubMed=18790866; DOI=10.1128/JB.00746-08;
RA Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H.,
RA Cha S.S., Kwon K.K., Kim H.T., Park C.J., Lee H.W., Kim S.I., Chun J.,
RA Colwell R.R., Kim S.J., Lee J.H.;
RT "The complete genome sequence of Thermococcus onnurineus NA1 reveals a
RT mixed heterotrophic and carboxydotrophic metabolism.";
RL J. Bacteriol. 190:7491-7499(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000855; ACJ17079.1; -; Genomic_DNA.
DR RefSeq; WP_012572551.1; NC_011529.1.
DR AlphaFoldDB; B6YTY8; -.
DR STRING; 523850.TON_1589; -.
DR GeneID; 7018628; -.
DR KEGG; ton:TON_1589; -.
DR PATRIC; fig|523850.10.peg.1602; -.
DR eggNOG; arCOG01537; Archaea.
DR HOGENOM; CLU_007100_9_5_2; -.
DR OrthoDB; 371891at2157; -.
DR Proteomes; UP000002727; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR42703:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT D1; 1.
DR PANTHER; PTHR42703; NADH DEHYDROGENASE; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 482..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..121
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 138..450
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 532 AA; 57498 MW; 7AEA4EB239840448 CRC64;
MNGEAILPYL IIIPLFGAFA MPIVNLAGKK AREAWAVLIS ALTFIVSSVI FYHIWNTGEI
IVYTLGAETP FGQGVDFPIR IVWEVDLFGA IMVFIVAFVS LMAVIYSIGY MKHDTGLDKY
YTLILILELG MLGIAITGDL FNFYVFLEIM SIASYALVAF RNDTWEGIEA GIKYMFVGSI
ASAFVLLGIA LLYGQYGTLT MGYLAVKIVQ NPTVTAKVAL ALFIAGLLFK SGASPVHMWL
ADAHPAAPSS ISAMLSGLVI KIGGIYAIAR ILFSIYTPMA HSIVLEAYLQ PHINMSAIGW
IIIIFACLTL IIGNAMAVIQ TDMKRLLAYS SVGQIGYILL GLGISIAAYG TQTGEIALAG
AIYHTVNHAL MKALLFLVAG VVIHQLGTRN LNELSGLAKT MPKTTFAFLI GAAAIVGMPP
LNGFASKWLI YESSAIFNPI LGAIAIIGTA FCTAAYVRVL YTFFGRPSEK VMAAKDPETS
MMLPMLLLVL AIIIMGLLPW QISDKVMIPA ARMLEQFRFE YINALMSLVG GA
//
