ID   B6YWG2_THEON            Unreviewed;       925 AA.
AC   B6YWG2;
DT   20-JAN-2009, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2009, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Large helicase-related protein {ECO:0000313|EMBL:ACJ16425.1};
GN   OrderedLocusNames=TON_0937 {ECO:0000313|EMBL:ACJ16425.1};
OS   Thermococcus onnurineus (strain NA1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Thermococcus.
OX   NCBI_TaxID=523850 {ECO:0000313|EMBL:ACJ16425.1, ECO:0000313|Proteomes:UP000002727};
RN   [1] {ECO:0000313|EMBL:ACJ16425.1, ECO:0000313|Proteomes:UP000002727}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA1 {ECO:0000313|EMBL:ACJ16425.1,
RC   ECO:0000313|Proteomes:UP000002727};
RX   PubMed=18790866; DOI=10.1128/JB.00746-08;
RA   Lee H.S., Kang S.G., Bae S.S., Lim J.K., Cho Y., Kim Y.J., Jeon J.H.,
RA   Cha S.S., Kwon K.K., Kim H.T., Park C.J., Lee H.W., Kim S.I., Chun J.,
RA   Colwell R.R., Kim S.J., Lee J.H.;
RT   "The complete genome sequence of Thermococcus onnurineus NA1 reveals a
RT   mixed heterotrophic and carboxydotrophic metabolism.";
RL   J. Bacteriol. 190:7491-7499(2008).
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DR   EMBL; CP000855; ACJ16425.1; -; Genomic_DNA.
DR   RefSeq; WP_012571897.1; NC_011529.1.
DR   AlphaFoldDB; B6YWG2; -.
DR   STRING; 523850.TON_0937; -.
DR   GeneID; 7017240; -.
DR   KEGG; ton:TON_0937; -.
DR   PATRIC; fig|523850.10.peg.945; -.
DR   eggNOG; arCOG00557; Archaea.
DR   HOGENOM; CLU_002025_0_0_2; -.
DR   OrthoDB; 33870at2157; -.
DR   Proteomes; UP000002727; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR017170; Lhr-like_ATP-dep_RNA_helic_prd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   PIRSF; PIRSF037307; Lhr-like_helic_prd; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:ACJ16425.1};
KW   Hydrolase {ECO:0000313|EMBL:ACJ16425.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          24..199
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          234..378
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   925 AA;  106479 MW;  36F026260301625F CRC64;
     MHLLLKKTIR ERFGKLNELQ MKAFREVSSG KSVLIIAPTG SGKTEAAVLP VFNAILEEGL
     KPISALYIAP LKALNRDLLE RLEWWGKRLG ISVEVRHGDT SAYKKAKQTK NPPQMLIITP
     ETLGVILTVK SLRKALENVK FVIVDEIAEL VDNKRGAQLL LNLERLVEIA DFKRIGMTAT
     VGNEDEVREW LGAETIVKPS WRKAYRFHVL YPRPEEKDFK LAEELSLAPD VAARLRTLWE
     IVEEHGKALI FTNTRQFAEI LAHRLKAWGK PVEVHHGSLS KEARIKAERA LKEGKIKALI
     CTSSMELGID IGDVDVVIQY MSPRQVNRLV QRVGRAKHRI GEVSEGYVIT SNVEDYLQSL
     IIARRALEGR FEAVEPIGGL DVLAHFLVGL LIEYKRMPRE RPYEIARRAY VYRELKWEEY
     LDVLGILEDA RLIGYDKEKN LLYLRRGAFQ YYYENLSTIP DEVSWRVFDS GSGHIIGRLD
     ESFVMDLEEG MEFVMNGRSW IVLKIDEEAK LLRVRESKSL ESAIPSWEGE MIPVPFGIAL
     DVGRLKRELT FDFKRALELL EGVDFSEVEL RRAFEEIKDG PFSTDRDIVI ESTPKALVIH
     ADFGNRANEA LGRLVHSFLI LRYGRVFSVR SQAHAIVFKT PFQLNPSEVK RYLYQEPEAL
     EFIVARSLRD SHAYRWRMMN VAKRFGALRR DAKIRRIERL FEGTVIEREA LNELYHDKVD
     VKRGELVLSM LKAGSLRVKT ELRREPSRLA RLNMSVGGEF LIGGELERDE ILELFKRRLL
     DHEVVLVCTN CGWSSKTRVS RLRERIKHWE CPKCGSRMLA VAHPIDAEEF MPILKKVRHG
     ERLERKEERA YRKLLKAADL IDSYGFDAVL ALASYGTGPD TAARLLSQYR GEALLVALME
     RERQFIRTRR FWVDAKKEEE KKSEE
//