ID B7G4J8_PHATC Unreviewed; 564 AA.
AC B7G4J8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Pyrophosphate-dependent phosphofructose kinase {ECO:0000313|EMBL:EEC46626.1};
GN Name=PFK1 {ECO:0000313|EMBL:EEC46626.1};
GN ORFNames=PHATRDRAFT_47690 {ECO:0000313|EMBL:EEC46626.1};
OS Phaeodactylum tricornutum (strain CCAP 1055/1).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae;
OC Phaeodactylum.
OX NCBI_TaxID=556484 {ECO:0000313|EMBL:EEC46626.1, ECO:0000313|Proteomes:UP000000759};
RN [1] {ECO:0000313|EMBL:EEC46626.1, ECO:0000313|Proteomes:UP000000759}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCAP 1055/1 {ECO:0000313|EMBL:EEC46626.1,
RC ECO:0000313|Proteomes:UP000000759};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
RN [2] {ECO:0000313|Proteomes:UP000000759}
RP GENOME REANNOTATION.
RC STRAIN=CCAP 1055/1 {ECO:0000313|Proteomes:UP000000759};
RG Diatom Consortium;
RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., Detter J.C.,
RA Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., Pitluck S.,
RA Rokhsar D., Bowler C.;
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; CM000616; EEC46626.1; -; Genomic_DNA.
DR RefSeq; XP_002182086.1; XM_002182050.1.
DR AlphaFoldDB; B7G4J8; -.
DR STRING; 556484.B7G4J8; -.
DR PaxDb; 2850-Phatr14284; -.
DR EnsemblProtists; Phatr3_J14284.t1; Phatr3_J14284.p1; Phatr3_J14284.
DR GeneID; 7202698; -.
DR KEGG; pti:PHATRDRAFT_47690; -.
DR eggNOG; KOG2440; Eukaryota.
DR HOGENOM; CLU_020655_7_4_1; -.
DR InParanoid; B7G4J8; -.
DR OMA; IGIRRGW; -.
DR OrthoDB; 995926at2759; -.
DR UniPathway; UPA00109; UER00182.
DR Proteomes; UP000000759; Chromosome 14.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.450; -; 1.
DR InterPro; IPR022953; ATP_PFK.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR InterPro; IPR035966; PKF_sf.
DR PANTHER; PTHR45770; ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1; 1.
DR PANTHER; PTHR45770:SF11; ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 1; 1.
DR Pfam; PF00365; PFK; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Phosphofructokinase; 1.
PE 4: Predicted;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EEC46626.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000759};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 184..491
FT /note="Phosphofructokinase"
FT /evidence="ECO:0000259|Pfam:PF00365"
FT REGION 543..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 62266 MW; 308961F93477DA52 CRC64;
MSKEHGQSLW YATALWLTTV VVTAAATYTV TKRREDAKQT AIVYRQYQRD KMLKEKTAEA
RKKSYEPPSG SLLDDLTLDK IYLWECEDLR KKFPSAMTEN TMKCKATPAP LIRSPTLRRS
YTAELDESDF ETAEKITRYN KLITDHECIL ADIVRKPNMH THTVSYMRAG PRRHLHFDPQ
SVNAAIVTCG GLCPGLNNVI REITKTLHQI YGIEGTVYGI QGGFRGFYDP APHLQPVILT
PELVENIHHE GGTVLGSSRG GFDIEKIRNF IHKHKINNLY VIGGDGTHRG AFRIHEDCME
HGMNVAVAGI PKTIDNDVDY IDHSFGFNSA VEAAQYAIRS AKTEAVCNLP NGIGIVKLMG
RSAGFIAAHA TMASSDVDLC LVPEVPTVLE GPNGCLPHLM RRVKQQGYAV VVVAEGAGEE
VLGISAEADA SGNKKLPAIG EFMKQAVTDF FAKHGDVATV KYIDPSYTVR SVPANAADSL
YCMQLAQNAV HGAMAGFTGF SVGLCNNRMV WLPIPELVAT SPRSMNPRGR TWERVLALTR
QPNTVQPLKK GEKDKYDSHS PMLR
//
