ID B7IE77_THEAB Unreviewed; 201 AA.
AC B7IE77;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Bifunctional purine biosynthesis protein PurH {ECO:0000313|EMBL:ACJ76304.1};
GN OrderedLocusNames=THA_1878 {ECO:0000313|EMBL:ACJ76304.1};
OS Thermosipho africanus (strain TCF52B).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Fervidobacteriaceae;
OC Thermosipho.
OX NCBI_TaxID=484019 {ECO:0000313|EMBL:ACJ76304.1, ECO:0000313|Proteomes:UP000002453};
RN [1] {ECO:0000313|EMBL:ACJ76304.1, ECO:0000313|Proteomes:UP000002453}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TCF52B {ECO:0000313|EMBL:ACJ76304.1,
RC ECO:0000313|Proteomes:UP000002453};
RX PubMed=19124572; DOI=10.1128/JB.01448-08;
RA Nesboe C.L., Bapteste E., Curtis B., Dahle H., Lopez P., Macleod D.,
RA Dlutek M., Bowman S., Zhaxybayeva O., Birkeland N.-K., Doolittle W.F.;
RT "The genome of Thermosipho africanus TCF52B: lateral genetic connections to
RT the Firmicutes and Archaea.";
RL J. Bacteriol. 191:1974-1978(2009).
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DR EMBL; CP001185; ACJ76304.1; -; Genomic_DNA.
DR RefSeq; WP_004102877.1; NC_011653.1.
DR AlphaFoldDB; B7IE77; -.
DR STRING; 484019.THA_1878; -.
DR KEGG; taf:THA_1878; -.
DR eggNOG; COG0138; Bacteria.
DR HOGENOM; CLU_016316_2_1_0; -.
DR OrthoDB; 9802065at2; -.
DR Proteomes; UP000002453; Chromosome.
DR GO; GO:0003937; F:IMP cyclohydrolase activity; IEA:InterPro.
DR GO; GO:0004643; F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd01421; IMPCH; 1.
DR Gene3D; 3.40.50.1380; Methylglyoxal synthase-like domain; 1.
DR InterPro; IPR011607; MGS-like_dom.
DR InterPro; IPR036914; MGS-like_dom_sf.
DR InterPro; IPR002695; PurH-like.
DR PANTHER; PTHR11692:SF0; BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC; 1.
DR PANTHER; PTHR11692; BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH; 1.
DR Pfam; PF01808; AICARFT_IMPCHas; 1.
DR Pfam; PF02142; MGS; 1.
DR SMART; SM00851; MGS; 1.
DR SUPFAM; SSF52335; Methylglyoxal synthase-like; 1.
DR PROSITE; PS51855; MGS; 1.
PE 4: Predicted;
FT DOMAIN 1..145
FT /note="MGS-like"
FT /evidence="ECO:0000259|PROSITE:PS51855"
SQ SEQUENCE 201 AA; 22592 MW; F0CBD100D04680A0 CRC64;
MNVKRALISV YNKEGIVEFA KKLSEWGVEI ISTGNTANLL EENGIPVIRV SEVTGFPEIL
GGRVKTLHPK IFGGILAKFG DSKHMKDLSD NNIKPIDMVV VNLYPFELVA KETRNEEKLI
ENIDIGGVAL LRAAAKNYRD VIVISDPEDY DKVLKSLEEC GDVILHQRRI LALKAFYRTM
KYDAEIHSVL SELFASNNFE E
//
