ID   B7J5Q7_ACIF2            Unreviewed;       227 AA.
AC   B7J5Q7;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   SubName: Full=MotA/TolQ/ExbB proton channel family protein {ECO:0000313|EMBL:ACK79001.1};
GN   OrderedLocusNames=AFE_2270 {ECO:0000313|EMBL:ACK79001.1};
OS   Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768
OS   / NCIMB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270)).
OC   Bacteria; Pseudomonadota; Acidithiobacillia; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=243159 {ECO:0000313|EMBL:ACK79001.1, ECO:0000313|Proteomes:UP000001362};
RN   [1] {ECO:0000313|EMBL:ACK79001.1, ECO:0000313|Proteomes:UP000001362}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
RC   {ECO:0000313|Proteomes:UP000001362};
RX   PubMed=19077236; DOI=10.1186/1471-2164-9-597;
RA   Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H., Blake R.II.,
RA   Eisen J.A., Holmes D.S.;
RT   "Acidithiobacillus ferrooxidans metabolism: from genome sequence to
RT   industrial applications.";
RL   BMC Genomics 9:597-597(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU004057}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU004057}.
CC   -!- SIMILARITY: Belongs to the exbB/tolQ family.
CC       {ECO:0000256|RuleBase:RU004057}.
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DR   EMBL; CP001219; ACK79001.1; -; Genomic_DNA.
DR   RefSeq; WP_009564717.1; NC_011761.1.
DR   AlphaFoldDB; B7J5Q7; -.
DR   STRING; 243159.AFE_2270; -.
DR   PaxDb; 243159-AFE_2270; -.
DR   GeneID; 66433022; -.
DR   KEGG; afr:AFE_2270; -.
DR   eggNOG; COG0811; Bacteria.
DR   HOGENOM; CLU_053325_4_4_6; -.
DR   Proteomes; UP000001362; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR   PANTHER; PTHR30625:SF9; MOTA_TOLQ_EXBB PROTON CHANNEL FAMILY PROTEIN; 1.
DR   PANTHER; PTHR30625; PROTEIN TOLQ; 1.
DR   Pfam; PF01618; MotA_ExbB; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Protein transport {ECO:0000256|RuleBase:RU004057};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001362};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|RuleBase:RU004057}.
FT   DOMAIN          75..192
FT                   /note="MotA/TolQ/ExbB proton channel"
FT                   /evidence="ECO:0000259|Pfam:PF01618"
FT   REGION          205..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..220
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   227 AA;  24742 MW;  5012CA057BAC577D CRC64;
     MNLQYLIHLA NYSDGVLYVL GALLLVELSV IVDRFWFLRR TILRGLIFVH ELGSHGRLDR
     DTLNQMADGA SDLPEAALLR MAASHHGQVK GEGLASRLEE SVLVLAPQLD RRLWLLDTII
     TLAPLLGLFG TIIGMFHAFS VLATPGHAPT AVTGGVADAL VATATGLFIA MLGLMAFNAF
     NNQVRQILLQ LDSVKTMLLN RMDGQPMITP DNSDKQRSEM LSVARAS
//