ID B7J5S9_ACIF2 Unreviewed; 705 AA.
AC B7J5S9;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Cytochrome o ubiquinol oxidase, subunit I {ECO:0000313|EMBL:ACK80009.1};
DE EC=1.10.3.- {ECO:0000313|EMBL:ACK80009.1};
GN Name=cyoB {ECO:0000313|EMBL:ACK80009.1};
GN OrderedLocusNames=AFE_0632 {ECO:0000313|EMBL:ACK80009.1};
OS Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768
OS / NCIMB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270)).
OC Bacteria; Pseudomonadota; Acidithiobacillia; Acidithiobacillales;
OC Acidithiobacillaceae; Acidithiobacillus.
OX NCBI_TaxID=243159 {ECO:0000313|EMBL:ACK80009.1, ECO:0000313|Proteomes:UP000001362};
RN [1] {ECO:0000313|EMBL:ACK80009.1, ECO:0000313|Proteomes:UP000001362}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
RC {ECO:0000313|Proteomes:UP000001362};
RX PubMed=19077236; DOI=10.1186/1471-2164-9-597;
RA Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H., Blake R.II.,
RA Eisen J.A., Holmes D.S.;
RT "Acidithiobacillus ferrooxidans metabolism: from genome sequence to
RT industrial applications.";
RL BMC Genomics 9:597-597(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
CC {ECO:0000256|RuleBase:RU000370}.
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DR EMBL; CP001219; ACK80009.1; -; Genomic_DNA.
DR AlphaFoldDB; B7J5S9; -.
DR STRING; 243159.AFE_0632; -.
DR PaxDb; 243159-AFE_0632; -.
DR KEGG; afr:AFE_0632; -.
DR eggNOG; COG0843; Bacteria.
DR HOGENOM; CLU_011899_7_1_6; -.
DR Proteomes; UP000001362; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
DR Gene3D; 1.20.210.10; Cytochrome c oxidase-like, subunit I domain; 1.
DR InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
DR InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
DR InterPro; IPR000883; Cyt_C_Oxase_1.
DR InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
DR PANTHER; PTHR10422:SF35; CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 1; 1.
DR PANTHER; PTHR10422; CYTOCHROME C OXIDASE SUBUNIT 1; 1.
DR Pfam; PF00115; COX1; 1.
DR PRINTS; PR01165; CYCOXIDASEI.
DR SUPFAM; SSF81442; Cytochrome c oxidase subunit I-like; 1.
DR PROSITE; PS50855; COX1; 1.
DR PROSITE; PS00077; COX1_CUB; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Electron transport {ECO:0000256|RuleBase:RU000370};
KW Heme {ECO:0000256|RuleBase:RU000370}; Iron {ECO:0000256|RuleBase:RU000370};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|RuleBase:RU000370};
KW Oxidoreductase {ECO:0000313|EMBL:ACK80009.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001362};
KW Respiratory chain {ECO:0000256|RuleBase:RU000370};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000370};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000370}.
FT TRANSMEM 16..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 592..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..566
FT /note="Cytochrome oxidase subunit I profile"
FT /evidence="ECO:0000259|PROSITE:PS50855"
SQ SEQUENCE 705 AA; 78427 MW; A04A503C3CB67C1D CRC64;
MLGRLAWSQI PYDNPILAPL FVAVVIGAIL VLGLITYYGK WTYLWKEWLT TVDHKKLGVM
YILIGLVMLF RGFIDGLMIR TQQAWAVGPH SSGVFGATHG YLTPFHFGQV YSAHGVIMIL
LAATPLLVGF MNIIVPIQIG ARDMAYPYLN ALGLWFTAAA GALIMISLFV GDFAHNGWFG
YAPIFELQYS PGVGVDYWIW TMELLALGTT LGGINILATI IKMRAPGMTW GRLPIFVWAS
IASNVIALTS FPALQVALAL VAADRYLGAH FFTAGLGGNL MLYTNLFWIW GHPEVYFVIL
PAFGMMSEIF PTFSEKPLFG YMTMVLASMA IAGVSWLVWL HHFFTMGAGP YVNSAFSVAT
MLVGIPTGVK VFNWAFTMYR GRLTFNAAML WAIGALFLLL VGGLTGMMLA VPAINYMVHN
SVFVVAHFHS MLLTIVYAIF ASVIYWFPKV FGFKLNEFWA KTMFWLFSAG TVLVFVPMYM
LGFMGMTRRL DYVFNTAWHP YLLVMEFGIV VYTLSVLAFF ALLYVSVRDH ASNQVGADAW
GTSRSLEWLT HSPVPFYNFA VLPHINARDE VAWRRDNGID HVQPDHYEDI HMPNNTGVAI
VLGGLTFVLG FALVWRIWWL CAFSLLAIIA LVIYRSFKGD PGYIITAAEL EQMEKAAMRR
EAGIGKQQHR VGGGVLGEAI AYERSDLPPL ASQPSSSVGL DHHRS
//
