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Database: UniProt
Entry: B7J758_ACIF2
LinkDB: B7J758_ACIF2
Original site: B7J758_ACIF2 
ID   B7J758_ACIF2            Unreviewed;       766 AA.
AC   B7J758;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 68.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   Name=feoB {ECO:0000313|EMBL:ACK79582.1};
GN   OrderedLocusNames=AFE_2524 {ECO:0000313|EMBL:ACK79582.1};
OS   Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP
OS   104768 / NCIMB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270)).
OC   Bacteria; Proteobacteria; Acidithiobacillia; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=243159 {ECO:0000313|EMBL:ACK79582.1, ECO:0000313|Proteomes:UP000001362};
RN   [1] {ECO:0000313|EMBL:ACK79582.1, ECO:0000313|Proteomes:UP000001362}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455
RC   {ECO:0000313|Proteomes:UP000001362};
RX   PubMed=19077236; DOI=10.1186/1471-2164-9-597;
RA   Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H.,
RA   Blake R.II., Eisen J.A., Holmes D.S.;
RT   "Acidithiobacillus ferrooxidans metabolism: from genome sequence to
RT   industrial applications.";
RL   BMC Genomics 9:597-597(2008).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CP001219; ACK79582.1; -; Genomic_DNA.
DR   STRING; 243159.AFE_2524; -.
DR   PaxDb; B7J758; -.
DR   EnsemblBacteria; ACK79582; ACK79582; AFE_2524.
DR   KEGG; afr:AFE_2524; -.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   HOGENOM; HOG000054023; -.
DR   KO; K04759; -.
DR   OMA; MEMPDYE; -.
DR   Proteomes; UP000001362; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001362};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001362};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    273    297       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    309    331       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    343    363       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    383    405       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    417    443       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    449    469       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    507    528       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    657    680       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    692    715       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    727    748       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        1    168       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   766 AA;  82338 MW;  35732F746AB91DD3 CRC64;
     MPVIALAGNP NCGKTTLFNL LTGAHQHVGN WPGVTVERRS GTMTLGRRKI SVVDLPGIYS
     LMGGGGEDQR VARDFLLDSD IELIVNIVDA SNLERHMALT AELLETGRPM VLVLNMVDEA
     EAHGLQVRSH ELSAAMGIPV IPTVARKARS RISLMEALTQ ALDHPALGNM LDYGQLIEAA
     LTALGTLLPG DPPAHRRFTA LCLLEGNIDP ADPKTQHALR QISSELAGTS DETPADLIMD
     RRFAWAQEMA TIALHRQGPA GLRQKITDRL DRVVLNDWLG VPVFLAVLYL VFVVSFSGGN
     VFLDFFDQAS AALLIHGVGH VLLGAGLPTW LVSIIAGGIG GGLNLVISFI PPIGLTFLFL
     AFLDDSGYMA RAAYAMDRLM RRMSLPGNAL VPMVIGFGCN VPAIMGSRII EDPRGRILTV
     LMQPFMSCSA RLTIYMAFAV VFFRSNGGQV VFALYVLGII VALLTAWLLG KTALRGEVLP
     FVMELPPYRL PSFRSVFLQA WQRLKVFIFR VGRVIAVIGV VLFILPGIGW TDRGLRSTDI
     DHSLLAQGSR ALVPIFEPMG IHQDNWPAIS GLIAGAAAKE IVIGTLNGIY QRQNAADLMA
     DYRDPDIAGQ LLGAIKTIPA NAVTFFTTLD DPLGLSAMDS TGTAEQASGA ESATLQAIAA
     GFTPLSAFAY LVFVLLYVPC ASTMGALRRE VGWGWMSFSL LYGTGLAWSA STVIYQSGTF
     AKHPGYSAAW IAGVLAAFAL LVVGLRLYGQ RSDALSKPSQ HRRASA
//
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