ID B7JXD6_RIPO1 Unreviewed; 230 AA.
AC B7JXD6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN OrderedLocusNames=PCC8801_3144 {ECO:0000313|EMBL:ACK67124.1};
OS Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS 8801)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK67124.1, ECO:0000313|Proteomes:UP000008204};
RN [1] {ECO:0000313|Proteomes:UP000008204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA Sherman L.A., Pakrasi H.B.;
RT "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT unicellular nitrogen-fixing Cyanobacteria.";
RL MBio 2:E214-E214(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001287; ACK67124.1; -; Genomic_DNA.
DR RefSeq; WP_012596385.1; NC_011726.1.
DR AlphaFoldDB; B7JXD6; -.
DR STRING; 41431.PCC8801_3144; -.
DR KEGG; cyp:PCC8801_3144; -.
DR eggNOG; COG0693; Bacteria.
DR HOGENOM; CLU_070319_2_0_3; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000008204; Chromosome.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008204};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 25..222
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
FT REGION 45..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 230 AA; 25165 MW; D8928691858929C0 CRC64;
MKKVLFVITS HDQLGETGQK TGFWLEEAVN PYYRFLDAGF EVTLTSPKGG EPPMDEKSTR
DEWQTEDTRR FFQDTTAQER FKNTVPLGQV NAADYDAIFL PGGHGPMWDL CQEQKLAQLV
EEFDRAGKII AAVCHGPAGL VSAKKPDGTP FVAGKKVTAF TNSEETTVGL HEVVPFMLET
HLCDLGAEFV KAEDFQEKVV QDGNLITGQN PASSTAAAKA VIDALSLVRA
//
