ID B7K3J6_RIPO1 Unreviewed; 1090 AA.
AC B7K3J6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=PCC8801_1273 {ECO:0000313|EMBL:ACK65338.1};
OS Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS 8801)).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK65338.1, ECO:0000313|Proteomes:UP000008204};
RN [1] {ECO:0000313|Proteomes:UP000008204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA Sherman L.A., Pakrasi H.B.;
RT "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT unicellular nitrogen-fixing Cyanobacteria.";
RL MBio 2:E214-E214(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001287; ACK65338.1; -; Genomic_DNA.
DR RefSeq; WP_012594612.1; NC_011726.1.
DR AlphaFoldDB; B7K3J6; -.
DR STRING; 41431.PCC8801_1273; -.
DR KEGG; cyp:PCC8801_1273; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_000445_114_15_3; -.
DR OrthoDB; 502671at2; -.
DR Proteomes; UP000008204; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 3.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ACK65338.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000008204};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 33..105
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 109..161
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 155..210
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 228..280
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 454..507
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 524..582
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 600..848
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 874..990
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 566..596
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 923
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1090 AA; 124112 MW; 902B77FF90D327FC CRC64;
MSEQIIKQLQ QEIATLKAVQ QATLKIQQEL QESQERWQLI IQATNEGIWD WNLRTNELFI
SPRWKEMLGY QDQELPNRFD TWKQLLHPQD VERVMEAVQN HLEGQTNHYQ IEFRLRCQDG
NYKWILSKGK ALWNSAGKAI RMVGSHSDIS DRKEEQILLR SLIDSIPDLI FCKDAQGVYK
ICNNAFEAFV GKPSQEIVGK TDFDLFPPEE ALFFRENDRI MREKKRPHRN EEWITYPDGS
RRLLDTLKTP FCCSEGKLMG VIGISRDITD RKQKENTVKK QAKRDSLLSS IARQLIDQDF
NTAVNFTLEA LGHFTDGDRG YIIRYSPQQR LWNMTHEWCN YQVPSTLQQS QNIPVEYLPW
FSRQLLNGQP ICVNSLDDLP PQAIAERVVF KNSLNPTLVV VPMVTAGQTV GYLGFDANSS
KIWTQEEVNL LKLVGEFIAI AQARSQAEDD RKESEARFAG ILDNANEAII SIDEQQQITL
FNHAAEKTFG YQAVNVLGQP FNQLIPPRFQ DSHYQYVEDF STCLETSRQM VGRRPVFGRR
QDGSEFLAEV SISKIQLKGR KLFTAIVRDI TERQQAEEAL KQAKEAADAA NRAKSEFLAS
MSHELRTPLN AILGFTQVMR RDRTLNPEHQ QNLSIISRSG EHLLELINDI LEMSKIEAGR
TTFHSNSFDL YRLLDNLEAM LHLKAQEKGL QLIFERTPEV PQYLETDEGK LRQVLINLLG
NAIKFTEEGG VTLRVKSEVR SRKGGFRESA TLRTIDLEKP ALTPIIADSE QIVITFEVED
SGPGIAPEEV DQLFAAFGQT ETGRQAQEGT GLGLPISRKF VQLMGGNISV SSILGQGSLF
AFSIKAKLTN ASAIKTPKPI RKVVGLAPGQ PQYRILSVDD RLESRLLLVK LLSSMGFEVR
QASNGKEALE IWETWEPHLI WMDMRMPIID GYQATQRIKA TTKGQGTVVI ALTASAFEEE
RNMVLSAGCD DFMRKPFREE VLWEKIAQHL GVRYIYESLE LEQAQGREIE ENPTDNPDYL
LKLLSQMSPD WVNQLHQVAV ECSDDGILEL ISKIPSESQP LAITLKGWAD NFLFDQVIQL
TQNLLNKQAK
//
