ID B7P5L4_IXOSC Unreviewed; 547 AA.
AC B7P5L4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=Kelch-like protein diablo {ECO:0000256|ARBA:ARBA00013699};
GN ORFNames=IscW_ISCW015707 {ECO:0000313|EMBL:EEC01886.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC01886.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC01886.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW015707-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW015707-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010476364; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS641689; EEC01886.1; -; Genomic_DNA.
DR RefSeq; XP_002407653.1; XM_002407609.1.
DR AlphaFoldDB; B7P5L4; -.
DR STRING; 6945.B7P5L4; -.
DR PaxDb; 6945-B7P5L4; -.
DR EnsemblMetazoa; ISCW015707-RA; ISCW015707-PA; ISCW015707.
DR KEGG; isc:IscW_ISCW015707; -.
DR VEuPathDB; VectorBase:ISCI015707; -.
DR VEuPathDB; VectorBase:ISCP_015013; -.
DR VEuPathDB; VectorBase:ISCW015707; -.
DR HOGENOM; CLU_004253_14_3_1; -.
DR InParanoid; B7P5L4; -.
DR OMA; PTNMRGM; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd14733; BACK; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 3.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 42..98
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 547 AA; 61194 MW; CE157F3D350E6F14 CRC64;
MKEISKQTDT GPAFRMVHFE SQPHANILLN GLNSLRARGQ LLDVTLIAGG REFKAHRAVL
AACSDYFRAM FTDAMRESRQ PEICLNGVSA QGLRCLLERA LPYLQDQLDL ENCIDVATLA
ETYSLRRLRK RVYRFICTNL HQFAETAEFQ RLSPHQLEHL LACDFPARKL LSYICFSEIP
ASRLAQLWDS PVLQCLFSRR IPPHLSGIGG LPPPSLVNTR GMELVLLKVG GFGLSGVTNE
ITYYLPSAGR WKYLTSIPHV EQCNFGTAVL GNELYVVGGC FNQSLHQENV HPFGFRYNAL
TNEWSTMAPM HWERCRFALC VARGHLYAIG GAGEVVSDAD ATEDGEIRCE RYEPHSDTWV
PITPLPGART QHAGASWGPY LFISGGLSSD LVLSSLLRYD TRSDVWEVMP PMSIPRTDHC
MVVYGDRLLV CGGWHEDIAT GARVLAESVE AYDIRNNSWS SVTAVPTPRY HAGVAVLGSW
LYTVGGFHSD TTFDRASGIV ERFDLDGVLG WEEVESYPQD VWEHVCCTLF VPRCRDDLDV
IPDKTLM
//
