ID B7P5X8_IXOSC Unreviewed; 282 AA.
AC B7P5X8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Voltage-dependent anion-selective channel, putative {ECO:0000313|EMBL:EEC02000.1, ECO:0000313|EnsemblMetazoa:ISCW000781-PA};
GN ORFNames=IscW_ISCW000781 {ECO:0000313|EMBL:EEC02000.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC02000.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC02000.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW000781-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW000781-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the eukaryotic mitochondrial porin family.
CC {ECO:0000256|ARBA:ARBA00007780}.
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DR EMBL; ABJB010965009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS643021; EEC02000.1; -; Genomic_DNA.
DR RefSeq; XP_002408065.1; XM_002408021.1.
DR AlphaFoldDB; B7P5X8; -.
DR SMR; B7P5X8; -.
DR STRING; 6945.B7P5X8; -.
DR PaxDb; 6945-B7P5X8; -.
DR EnsemblMetazoa; ISCW000781-RA; ISCW000781-PA; ISCW000781.
DR KEGG; isc:IscW_ISCW000781; -.
DR VEuPathDB; VectorBase:ISCP_022023; -.
DR VEuPathDB; VectorBase:ISCW000781; -.
DR HOGENOM; CLU_044399_2_0_1; -.
DR InParanoid; B7P5X8; -.
DR OMA; KGYHFGV; -.
DR OrthoDB; 2897965at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IBA:GO_Central.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0008308; F:voltage-gated monoatomic anion channel activity; IBA:GO_Central.
DR CDD; cd07306; Porin3_VDAC; 1.
DR Gene3D; 2.40.160.10; Porin; 1.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR001925; Porin_Euk.
DR InterPro; IPR027246; Porin_Euk/Tom40.
DR PANTHER; PTHR11743:SF70; GH26960P-RELATED; 1.
DR PANTHER; PTHR11743; VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL; 1.
DR Pfam; PF01459; Porin_3; 1.
DR PRINTS; PR00185; EUKARYTPORIN.
PE 1: Evidence at protein level;
KW Ion transport {ECO:0000256|ARBA:ARBA00023114};
KW Membrane {ECO:0000256|ARBA:ARBA00022452};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Porin {ECO:0000256|ARBA:ARBA00023114};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7P5X8};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022452};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00023114}.
SQ SEQUENCE 282 AA; 30273 MW; 82C8079A32551942 CRC64;
MAPPCYADLG KQARDLFNKN YHFGVVKLDC KTTTKTGVEF NVSGTSLNDT GKVNASLETK
YKVSDLGLTL KEKWNTDNTL ATEISCDDQL ARGLKLAFNA NFAPQTGKKS GALKTAYKVD
NIHVNSDVDL GIGGPIAHAG AVLHYQGWLA GAQLSYDANK SRLSKTNFAV GYQGGDFVLH
TNVNDGQEFA GSIYQRVNDC LETGVQLSWT AGTNATRFGL GCVYQLDRET SVRAKVNNSG
QVGLGFTHRL RPGISLTLST MLDGKNFNQG GHKLGLGLDL SA
//
