ID B7P7V7_IXOSC Unreviewed; 219 AA.
AC B7P7V7;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 08-NOV-2023, entry version 66.
DE SubName: Full=B-cell translocation protein, putative {ECO:0000313|EMBL:EEC02679.1, ECO:0000313|EnsemblMetazoa:ISCW003220-PA};
GN Name=8025890 {ECO:0000313|EnsemblMetazoa:ISCW003220-PA};
GN ORFNames=IscW_ISCW003220 {ECO:0000313|EMBL:EEC02679.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC02679.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC02679.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW003220-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW003220-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BTG family. {ECO:0000256|ARBA:ARBA00007989}.
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DR EMBL; ABJB010347675; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010495731; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011108411; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS653761; EEC02679.1; -; Genomic_DNA.
DR RefSeq; XP_002399840.1; XM_002399797.1.
DR AlphaFoldDB; B7P7V7; -.
DR STRING; 6945.B7P7V7; -.
DR PaxDb; 6945-B7P7V7; -.
DR EnsemblMetazoa; ISCW003220-RA; ISCW003220-PA; ISCW003220.
DR GeneID; 8025890; -.
DR KEGG; isc:IscW_ISCW003220; -.
DR VEuPathDB; VectorBase:ISCI003220; -.
DR VEuPathDB; VectorBase:ISCP_016093; -.
DR VEuPathDB; VectorBase:ISCW003220; -.
DR HOGENOM; CLU_079660_3_0_1; -.
DR InParanoid; B7P7V7; -.
DR OMA; YCILASF; -.
DR OrthoDB; 11568at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IBA:GO_Central.
DR GO; GO:0045930; P:negative regulation of mitotic cell cycle; IBA:GO_Central.
DR Gene3D; 3.90.640.90; Anti-proliferative protein, N-terminal domain; 1.
DR InterPro; IPR002087; Anti_prolifrtn.
DR InterPro; IPR033332; BTG.
DR InterPro; IPR036054; BTG-like_sf.
DR PANTHER; PTHR22978; B-CELL TRANSLOCATION GENE; 1.
DR PANTHER; PTHR22978:SF44; PROTEIN BTG3-LIKE PROTEIN; 1.
DR Pfam; PF07742; BTG; 1.
DR PRINTS; PR00310; ANTIPRLFBTG1.
DR SMART; SM00099; btg1; 1.
DR SUPFAM; SSF160696; BTG domain-like; 1.
DR PROSITE; PS01203; BTG_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 86..105
FT /note="Anti-proliferative protein"
FT /evidence="ECO:0000259|PROSITE:PS01203"
SQ SEQUENCE 219 AA; 24790 MW; F2AA4C34883DEA7B CRC64;
MKDEVEAAVA FLIRVVGKNS RLEPGQLDAL RARLEAVLTD RFREHWFPER PSRGQAYRCI
RINEAREPVL EQASRQCGLS YEELCLPAEL TLWVDPDEVC CRFGERQSSY CILASFKGGK
KENYVDQINI DDLEQRSMER SKQASMDMMS GRKRAVGSQR GWGMKFPSYS PCLSGSPPGV
FSQPKFLSRG GTLWNLSAAL PPGQKPDKYH WVNKSVVKA
//
