ID B7P7X4_IXOSC Unreviewed; 181 AA.
AC B7P7X4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 08-NOV-2023, entry version 65.
DE SubName: Full=Aromatic amino acid hydroxlase, putative {ECO:0000313|EMBL:EEC02696.1};
DE EC=1.14.16.2 {ECO:0000313|EMBL:EEC02696.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW002330 {ECO:0000313|EMBL:EEC02696.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC02696.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel colony {ECO:0000313|EMBL:EEC02696.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DS654236; EEC02696.1; -; Genomic_DNA.
DR RefSeq; XP_002400150.1; XM_002400106.1.
DR AlphaFoldDB; B7P7X4; -.
DR STRING; 6945.B7P7X4; -.
DR PaxDb; 6945-B7P7X4; -.
DR KEGG; isc:IscW_ISCW002330; -.
DR VEuPathDB; VectorBase:ISCP_034258; -.
DR VEuPathDB; VectorBase:ISCW002330; -.
DR OMA; KESWILE; -.
DR PhylomeDB; B7P7X4; -.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004511; F:tyrosine 3-monooxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0009072; P:aromatic amino acid metabolic process; IEA:InterPro.
DR Gene3D; 1.10.800.10; Aromatic amino acid hydroxylase; 1.
DR InterPro; IPR001273; ArAA_hydroxylase.
DR InterPro; IPR036951; ArAA_hydroxylase_sf.
DR InterPro; IPR019774; Aromatic-AA_hydroxylase_C.
DR PANTHER; PTHR11473; AROMATIC AMINO ACID HYDROXYLASE; 1.
DR PANTHER; PTHR11473:SF15; TYROSINE 3-MONOOXYGENASE; 1.
DR Pfam; PF00351; Biopterin_H; 1.
DR PROSITE; PS51410; BH4_AAA_HYDROXYL_2; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:EEC02696.1}.
FT DOMAIN 140..181
FT /note="Biopterin-dependent aromatic amino acid hydroxylase
FT family profile"
FT /evidence="ECO:0000259|PROSITE:PS51410"
FT NON_TER 181
FT /evidence="ECO:0000313|EMBL:EEC02696.1"
SQ SEQUENCE 181 AA; 20506 MW; C1C35B7D8A7D1801 CRC64;
MDLRIFLWQH GYPSKRRSLL DDAKFETQKH KEAEEVRRQA SRDSQDTIDS LLEDVYFEDV
LSGGKDQTAS VVFGLRDGVE SLAKILKEVD DCGGKVNHLE TRTSKQPNQT HEVFVSMNIS
RDQLLGLAKA LALNTLADMR VIKDFSSAMA GDIWFPLHIS DLDFCTHVLT KFEPDLDSDH
P
//
