ID B7P835_IXOSC Unreviewed; 326 AA.
AC B7P835;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 79.
DE SubName: Full=Zinc-binding dehydrogenase, putative {ECO:0000313|EMBL:EEC02757.1, ECO:0000313|EnsemblMetazoa:ISCW024193-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW024193 {ECO:0000313|EMBL:EEC02757.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC02757.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC02757.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW024193-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW024193-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010104638; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS655177; EEC02757.1; -; Genomic_DNA.
DR RefSeq; XP_002400936.1; XM_002400892.1.
DR AlphaFoldDB; B7P835; -.
DR STRING; 6945.B7P835; -.
DR PaxDb; 6945-B7P835; -.
DR EnsemblMetazoa; ISCW024193-RA; ISCW024193-PA; ISCW024193.
DR KEGG; isc:IscW_ISCW024193; -.
DR VEuPathDB; VectorBase:ISCI002789; -.
DR VEuPathDB; VectorBase:ISCP_001577; -.
DR VEuPathDB; VectorBase:ISCW024193; -.
DR HOGENOM; CLU_026673_3_4_1; -.
DR InParanoid; B7P835; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08276; MDR7; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR45033; -; 1.
DR PANTHER; PTHR45033:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1773.06C; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 24..324
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC02757.1"
SQ SEQUENCE 326 AA; 35291 MW; 15CE68707BBBA91C CRC64;
PSLACSMQAS TGANMNSYRF MQYGSLDYLE LRQEPIPEPG PGQVRVQIMA SSLNFRDLLV
MKDTLRYPST PGAIPLSDAA GVIDALGPGV QRFKLGDQQY GIEHDGWLTQ YKVVSAEALS
LMPAHLSFEE AATLPCAALT AWSALEGTNA GDTVLTQGAG GVSTFVIQLA KAMGAHVISS
TSSDDKFDKL LQLGADKVFN YKDTPEWSEL VRHYTHGEGA NRIVDVGGPV TIAQSIKAVA
VGGQVSLVGS LGKSVESLDV MDLVFSQASY KAIGVGSRSD LEAMNRVISQ HRIHPVIDQV
FDFKNAHEAY RYLQQRHRFG KIVIHH
//
