ID B7P8D6_IXOSC Unreviewed; 301 AA.
AC B7P8D6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Salivary sulfotransferase, putative {ECO:0000313|EMBL:EEC02858.1, ECO:0000313|EnsemblMetazoa:ISCW016685-PA};
DE EC=2.8.2.2 {ECO:0000313|EMBL:EEC02858.1};
GN ORFNames=IscW_ISCW016685 {ECO:0000313|EMBL:EEC02858.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC02858.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC02858.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW016685-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW016685-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771}.
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DR EMBL; ABJB011123391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS656787; EEC02858.1; -; Genomic_DNA.
DR RefSeq; XP_002401861.1; XM_002401817.1.
DR AlphaFoldDB; B7P8D6; -.
DR PaxDb; 6945-B7P8D6; -.
DR EnsemblMetazoa; ISCW016685-RA; ISCW016685-PA; ISCW016685.
DR KEGG; isc:IscW_ISCW016685; -.
DR VEuPathDB; VectorBase:ISCI016685; -.
DR VEuPathDB; VectorBase:ISCP_025089; -.
DR VEuPathDB; VectorBase:ISCW016685; -.
DR HOGENOM; CLU_027239_2_1_1; -.
DR InParanoid; B7P8D6; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004027; F:alcohol sulfotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF334; SULFOTRANSFERASE SSU-1; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EEC02858.1}.
FT DOMAIN 38..290
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 301 AA; 34920 MW; 4AD0EDFD981FC84D CRC64;
MAAPRRVPAT QMIDGDICFI YFDPTLYREA PNFEPQDGDI IELTYPRCGS HWIQQIIQLV
LERGESAKTF DEFANRAPFL EMNELKPTKA PRLIRTHLPF GKIKFSRKAK YVYVARNPWD
CCVSCYHLIR ETPSCKFGDG TFDEFLEAFI RAEMGAGDYF DNLMAAYELR DEPIVFFVTY
EELQERKADV VLRLADFLGE DYGRCLREND DVFRRVMEKS TVSFMKEFLR PDQKQVLVQL
GKETGSADDS ETKAVLNLVR RGTVGDWKTH FSPENIETMQ AYIDAKTKGS EVMSLWKDFR
I
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