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Database: UniProt
Entry: B7P8L1_IXOSC
LinkDB: B7P8L1_IXOSC
Original site: B7P8L1_IXOSC 
ID   B7P8L1_IXOSC            Unreviewed;       328 AA.
AC   B7P8L1;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   16-OCT-2019, entry version 71.
DE   SubName: Full=Transcriptional repressor Yan, putative {ECO:0000313|EMBL:EEC02933.1};
DE   SubName: Full=Transcriptional repressor Yan, putative (Fragment) (Fragment) {ECO:0000313|VectorBase:ISCW002717-PA};
DE   Flags: Fragment;
GN   Name=8026193 {ECO:0000313|VectorBase:ISCW002717-PA};
GN   ORFNames=IscW_ISCW002717 {ECO:0000313|EMBL:EEC02933.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945 {ECO:0000313|Proteomes:UP000001555};
RN   [1] {ECO:0000313|EMBL:EEC02933.1, ECO:0000313|Proteomes:UP000001555, ECO:0000313|VectorBase:ISCW002717-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555,
RC   ECO:0000313|VectorBase:ISCW002717-PA}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC02933.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M.,
RA   Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J.,
RA   Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G.,
RA   Meyer J., Hill C.A., Birren B., Nene V., Collins F.,
RA   Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:ISCW002717-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|VectorBase:ISCW002717-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; ABJB010953442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS658362; EEC02933.1; -; Genomic_DNA.
DR   RefSeq; XP_002402447.1; XM_002402403.1.
DR   EnsemblMetazoa; ISCW002717-RA; ISCW002717-PA; ISCW002717.
DR   KEGG; isc:IscW_ISCW002717; -.
DR   VectorBase; ISCW002717-RA; ISCW002717-PA; ISCW002717.
DR   CTD; 8026193; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   InParanoid; B7P8L1; -.
DR   KO; K03211; -.
DR   OMA; RIQPSLW; -.
DR   OrthoDB; 827924at2759; -.
DR   PhylomeDB; B7P8L1; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0001709; P:cell fate determination; IEA:InterPro.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR033077; Pokkuri.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF201; PTHR11849:SF201; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001555};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT   DOMAIN        1     69       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      199    282       ETS. {ECO:0000259|PROSITE:PS50061}.
FT   REGION      126    176       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      301    328       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:EEC02933.1}.
SQ   SEQUENCE   328 AA;  36626 MW;  E5D9B8576593EC4A CRC64;
     NDPRQWSKHN VSMWLEWCTE QFSLVPTDAD NFHMNGKALC LLSKADFLER APKAGDVLFN
     ALQLLLHRAL HTARMHNGGG QGNGAVPRST VITRDVQGFG QVLLQDPASY NQCLQVSPLP
     AEVDSTVILS PDPSSGGESG EPKGASPSPP SCRHRSPSPA TPTFGPGGAT SPVPQQPLAL
     TTPAARVVAD APGDKMSVRL LWDFLQQLLN DPEQKYRHCI TWKDQAKGVF KITDPHRLAK
     LWGMQKNHLN MNFDKMSRAM RYYYRVKILQ KEPGERLCYR FLRPPTELRY CKQRSLLERT
     SERVEDEEAP GALDMSIKEE CSSPSHND
//
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