ID   B7P942_IXOSC            Unreviewed;       661 AA.
AC   B7P942;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   24-JAN-2024, entry version 72.
DE   RecName: Full=Spt20-like SEP domain-containing protein {ECO:0000259|Pfam:PF12090};
GN   ORFNames=IscW_ISCW017342 {ECO:0000313|EMBL:EEC03114.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945;
RN   [1] {ECO:0000313|EMBL:EEC03114.1, ECO:0000313|Proteomes:UP000001555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC03114.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA   Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA   Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA   Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ISCW017342-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW017342-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the SPT20 family.
CC       {ECO:0000256|ARBA:ARBA00009112}.
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DR   EMBL; ABJB010293611; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010342686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010470406; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010705712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS661587; EEC03114.1; -; Genomic_DNA.
DR   RefSeq; XP_002403583.1; XM_002403539.1.
DR   AlphaFoldDB; B7P942; -.
DR   STRING; 6945.B7P942; -.
DR   PaxDb; 6945-B7P942; -.
DR   EnsemblMetazoa; ISCW017342-RA; ISCW017342-PA; ISCW017342.
DR   KEGG; isc:IscW_ISCW017342; -.
DR   VEuPathDB; VectorBase:ISCI017342; -.
DR   VEuPathDB; VectorBase:ISCP_012435; -.
DR   VEuPathDB; VectorBase:ISCW017342; -.
DR   HOGENOM; CLU_020200_1_0_1; -.
DR   InParanoid; B7P942; -.
DR   OMA; GTHACHH; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0000124; C:SAGA complex; IBA:GO_Central.
DR   GO; GO:0003712; F:transcription coregulator activity; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR021950; Spt20.
DR   InterPro; IPR046468; Spt20-like_SEP.
DR   PANTHER; PTHR13526; TRANSCRIPTION FACTOR SPT20 HOMOLOG; 1.
DR   PANTHER; PTHR13526:SF8; TRANSCRIPTION FACTOR SPT20 HOMOLOG; 1.
DR   Pfam; PF12090; Spt20_SEP; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT   DOMAIN          76..248
FT                   /note="Spt20-like SEP"
FT                   /evidence="ECO:0000259|Pfam:PF12090"
FT   REGION          613..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        627..648
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  71406 MW;  522F6305453C628F CRC64;
     MSTNALAACL QQANHLIQTA RQQPGKLCRD QRKEKCPSLQ QRLTDLFLSE CSFNPRNKSL
     YSGSHLLSKL VSKEKLNCLV LNLYPGNEGY SLMLKTRTGT ETETVRLPYE EDELLRYIDN
     EELAPVLVDL LERSQVSAMI HGGVAGRASR GCHATQAPVF YSGCVIVEVR DHRRCSSSLG
     THACHHVLLK PTTQSVLCDV GLLVCQDGQG WSLEDRVSLE AALVLATSEP LCLEPSVGVA
     VLSNWMQHRK GRLSSHAVHR MARRQGQVAL NRRRKLERCA APACLRAHDF ISQYRKRVPL
     RATASSSNKQ ADVWKQKRAT MPVPQKIEVE RLASVRERPE PTSDPTPVVV QEYLLETEQT
     SGKLTQVTIL QRPTDEQFFG KLYVDRDGHS RGTSCEYLNQ FREIFTEEGR KPVKITHLVP
     GQAPVVKHTH GAPPPDLPSA STLCAKEPKP PVSIAAQPSE VVSLPNLSLT AQNMGLHNLV
     SLAGVNLSSG LPVPISLTMV PVTQSSVLVG TAGSLHAQEQ PGQQPQQPCA SQGASVGTSA
     VIVSSGMVNP ASTVLTSGSG VLSMPLRVTT LGTQALTAQL VGTGMEGTTQ GQPLSLLQVP
     GGQQTLIGTL PRHTMPAAGP TGGHGNPQLQ MALQKQLQRQ QGSTAPASAG RPRNRKKPGK
     T
//