ID B7P9R5_IXOSC Unreviewed; 208 AA.
AC B7P9R5;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Cytoglobin-1, putative {ECO:0000313|EMBL:EEC03337.1, ECO:0000313|EnsemblMetazoa:ISCW002312-PA};
GN ORFNames=IscW_ISCW002312 {ECO:0000313|EMBL:EEC03337.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC03337.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC03337.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW002312-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW002312-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the globin family.
CC {ECO:0000256|ARBA:ARBA00008705, ECO:0000256|PROSITE-ProRule:PRU00238,
CC ECO:0000256|RuleBase:RU000356}.
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DR EMBL; ABJB010671488; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS666390; EEC03337.1; -; Genomic_DNA.
DR RefSeq; XP_002405154.1; XM_002405110.1.
DR AlphaFoldDB; B7P9R5; -.
DR STRING; 6945.B7P9R5; -.
DR PaxDb; 6945-B7P9R5; -.
DR EnsemblMetazoa; ISCW002312-RA; ISCW002312-PA; ISCW002312.
DR KEGG; isc:IscW_ISCW002312; -.
DR VEuPathDB; VectorBase:ISCI002312; -.
DR VEuPathDB; VectorBase:ISCP_003058; -.
DR VEuPathDB; VectorBase:ISCP_029981; -.
DR VEuPathDB; VectorBase:ISCW002312; -.
DR HOGENOM; CLU_098781_1_0_1; -.
DR InParanoid; B7P9R5; -.
DR OMA; WKIEKPF; -.
DR OrthoDB; 2908767at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019825; F:oxygen binding; IBA:GO_Central.
DR GO; GO:0005344; F:oxygen carrier activity; IBA:GO_Central.
DR GO; GO:0015671; P:oxygen transport; IBA:GO_Central.
DR GO; GO:0001666; P:response to hypoxia; IBA:GO_Central.
DR CDD; cd14766; CeGLB25-like; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR PANTHER; PTHR46458; BLR2807 PROTEIN; 1.
DR PANTHER; PTHR46458:SF5; GLOBIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00042; Globin; 1.
DR SUPFAM; SSF46458; Globin-like; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000356}; Iron {ECO:0000256|RuleBase:RU000356};
KW Metal-binding {ECO:0000256|RuleBase:RU000356};
KW Oxygen transport {ECO:0000256|RuleBase:RU000356};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transport {ECO:0000256|RuleBase:RU000356}.
FT DOMAIN 49..194
FT /note="Globin family profile"
FT /evidence="ECO:0000259|PROSITE:PS01033"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..48
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 208 AA; 23433 MW; 53A232889E14B87E CRC64;
MGCTLSKTLS SLVRGSEGRK GSNSGTGGSE ADPVADPPPP PPPDPRQPLT ARQIFSISKS
WKAIARAMEP TGIEMFVRLF QEKEDLLDLF EKFQALRTKE SQRESMELAQ HASVVMTTLD
EGINALDNLD YFMSYLHNAG RLHYKIKGFK KEYFWHIEGP FLAAVSDTLG DRYTDNIENI
YKITIRFILQ TLIEGFEEAE KEAAQQAR
//
