ID B7PCC0_IXOSC Unreviewed; 485 AA.
AC B7PCC0;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Neural cell adhesion molecule L1, putative {ECO:0000313|EMBL:EEC04242.1, ECO:0000313|EnsemblMetazoa:ISCW017407-PA};
GN Name=8027799 {ECO:0000313|EnsemblMetazoa:ISCW017407-PA};
GN ORFNames=IscW_ISCW017407 {ECO:0000313|EMBL:EEC04242.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC04242.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC04242.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW017407-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW017407-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010337873; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010677504; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS682990; EEC04242.1; -; Genomic_DNA.
DR RefSeq; XP_002409638.1; XM_002409594.1.
DR AlphaFoldDB; B7PCC0; -.
DR PaxDb; 6945-B7PCC0; -.
DR EnsemblMetazoa; ISCW017407-RA; ISCW017407-PA; ISCW017407.
DR KEGG; isc:IscW_ISCW017407; -.
DR VEuPathDB; VectorBase:ISCI017407; -.
DR VEuPathDB; VectorBase:ISCP_037067; -.
DR VEuPathDB; VectorBase:ISCW017407; -.
DR HOGENOM; CLU_562954_0_0_1; -.
DR InParanoid; B7PCC0; -.
DR OMA; KHATESH; -.
DR OrthoDB; 3107289at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0030424; C:axon; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0098632; F:cell-cell adhesion mediator activity; IBA:GO_Central.
DR GO; GO:0007411; P:axon guidance; IBA:GO_Central.
DR GO; GO:0070593; P:dendrite self-avoidance; IBA:GO_Central.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IBA:GO_Central.
DR CDD; cd00063; FN3; 1.
DR CDD; cd20958; IgI_5_Dscam; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR10075; BASIGIN RELATED; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 50..135
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 142..234
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 239..332
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 348..431
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 435..485
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 485 AA; 52996 MW; 03097B048AE30A3C CRC64;
MGDYVTSDGS VVSFVNISAV RAEDGGLYRC SAGNDVGVSE HAARVNIHGP PFVRRMGNLS
VVAGEVLSIT CPVGGHPIDS ITWEREGLRL PYNHRQKAFP NGTLLVQDVE RATDEGLYSC
TARNKDGLSA QNSVSVRVLV RPAIVPFSFP ESLHQGQRFN VLCTVSKGDS PIHIAWYKDD
APVATTGAAA VSVLNVTQFS STLIFDKLVP EHRGNYTCEA RNQAGLVRAT STMVIHVPPR
WRIEPSDSIV VKGGTAIIDC QADGFPVPRV RWTKSEGNEP GDYRAISSSS RIHVFENGSL
AVHNSDEKDA GFFLCQASNG ISPVLSKVVK LSVHVAAHFK SKFKAESVQR GHLVKLKCEA
FGDKPVIITW TRDKQPFDPK EDPRYELNET LLSGGIVSEI TIRGADRRDS ALFTCLARNS
YGTDDTNMQL ILQEPPDSPP GVKLLEYGSR HVKLSWVTPY SGNSPVVKYV LQYREDSGKY
GKTSN
//
