ID B7PCZ2_IXOSC Unreviewed; 182 AA.
AC B7PCZ2;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Diacylglycerol kinase, putative {ECO:0000313|EMBL:EEC04464.1, ECO:0000313|EnsemblMetazoa:ISCW002929-PA};
DE EC=2.7.1.107 {ECO:0000313|EMBL:EEC04464.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW002929 {ECO:0000313|EMBL:EEC04464.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC04464.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC04464.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW002929-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW002929-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-
CC phosphate + ADP + H(+); Xref=Rhea:RHEA:10272, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17815, ChEBI:CHEBI:30616, ChEBI:CHEBI:58608,
CC ChEBI:CHEBI:456216; EC=2.7.1.107;
CC Evidence={ECO:0000256|ARBA:ARBA00001383};
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DR EMBL; ABJB010221985; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS686946; EEC04464.1; -; Genomic_DNA.
DR RefSeq; XP_002410451.1; XM_002410406.1.
DR AlphaFoldDB; B7PCZ2; -.
DR STRING; 6945.B7PCZ2; -.
DR PaxDb; 6945-B7PCZ2; -.
DR EnsemblMetazoa; ISCW002929-RA; ISCW002929-PA; ISCW002929.
DR KEGG; isc:IscW_ISCW002929; -.
DR VEuPathDB; VectorBase:ISCI002929; -.
DR VEuPathDB; VectorBase:ISCP_028337; -.
DR VEuPathDB; VectorBase:ISCW002929; -.
DR HOGENOM; CLU_101030_0_0_1; -.
DR InParanoid; B7PCZ2; -.
DR OMA; MQPPGRI; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007205; P:protein kinase C-activating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF48; DIACYLGLYCEROL KINASE 1; 1.
DR Pfam; PF00609; DAGK_acc; 1.
DR SMART; SM00045; DAGKa; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EEC04464.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EEC04464.1}.
FT DOMAIN 1..175
FT /note="Diacylglycerol kinase accessory"
FT /evidence="ECO:0000259|SMART:SM00045"
FT REGION 87..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC04464.1"
FT NON_TER 182
FT /evidence="ECO:0000313|EMBL:EEC04464.1"
SQ SEQUENCE 182 AA; 20451 MW; 5E6CE5287ED36F00 CRC64;
DASIAIKFHL EREKHPEKFS SRMKNKMWYF EFATSETFFA TCKNLHDDVD IMCDGVSLEL
SNGPSLQGIA VLNIPSIYGG SNLWGDNAAS RKRSRSKKRK KHDRDISTNS FNSVDLSSAV
QDIGDRMIEV IGLESSMHMG QVKAGLRASG RRLAQCTSVV IRTRKRFPMQ IDGEPWVQPP
CT
//
