ID B7PEB1_IXOSC Unreviewed; 1754 AA.
AC B7PEB1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Sdk-P1, putative {ECO:0000313|EMBL:EEC04933.1, ECO:0000313|EnsemblMetazoa:ISCW003491-PA};
DE EC=2.7.11.14 {ECO:0000313|EMBL:EEC04933.1};
GN ORFNames=IscW_ISCW003491 {ECO:0000313|EMBL:EEC04933.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC04933.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC04933.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW003491-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW003491-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010031046; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010214830; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010322287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010350102; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010401641; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010653739; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010772719; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010861238; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010959406; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011026718; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS694733; EEC04933.1; -; Genomic_DNA.
DR RefSeq; XP_002400783.1; XM_002400739.1.
DR STRING; 6945.B7PEB1; -.
DR PaxDb; 6945-B7PEB1; -.
DR EnsemblMetazoa; ISCW003491-RA; ISCW003491-PA; ISCW003491.
DR KEGG; isc:IscW_ISCW003491; -.
DR VEuPathDB; VectorBase:ISCI003491; -.
DR VEuPathDB; VectorBase:ISCP_017968; -.
DR VEuPathDB; VectorBase:ISCP_030581; -.
DR VEuPathDB; VectorBase:ISCP_037977; -.
DR VEuPathDB; VectorBase:ISCW003491; -.
DR HOGENOM; CLU_001875_1_0_1; -.
DR InParanoid; B7PEB1; -.
DR OMA; WFMVTLA; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0030424; C:axon; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0098632; F:cell-cell adhesion mediator activity; IBA:GO_Central.
DR GO; GO:0050254; F:rhodopsin kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0007411; P:axon guidance; IBA:GO_Central.
DR GO; GO:0070593; P:dendrite self-avoidance; IBA:GO_Central.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IBA:GO_Central.
DR CDD; cd00063; FN3; 9.
DR Gene3D; 2.60.40.10; Immunoglobulins; 14.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF48; MYOPALLADIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 7.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 9.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 6.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50853; FN3; 9.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PEB1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:EEC04933.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1560..1582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..106
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 218..292
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 303..395
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 397..483
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 488..575
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 560..654
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 659..764
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 768..854
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 859..954
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 959..1055
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1101..1197
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1202..1301
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1306..1400
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1404..1498
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 939..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1604..1724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1648..1663
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1664..1679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1754 AA; 190065 MW; 9B43943CBA2E08C4 CRC64;
MHSHILRSNR IQPRDFVEHQ WAPRFVKHPE GGYVSLGQRR GLHCDAVGSP APRLRLLRDG
QPLTNWTGTT RLLHVLSHVE LSHAGLYQCV ANNSAGSVLS RTAKLRVAHL TASEPVSKTV
TVQVRRGSPV VLDPPRAESV PAATATWMRL SGDASGSEPL EGIQYATTQD NHLVILEARF
EDQGRYQVEL TNPHTGEFLL GPLLELEVEG ESVEEDGPHK LSIVVPPSES EFNNLGNGYD
NTLECIAAGS PLEEVRVSWL KGGQPLRGLP HALTHWNRTL TLLNRLSEGP NYGGSLLWVA
VPPRLVQAVS EETAAELGQH LQLPCLAEGR PPPAVEWLRN ARPLDVAAGG RLHVLSNGSL
DIDALSMEDA GVLQCVAHNP LGEARAATWL HVKISPPAFL RPPENVTVLD GMDAQLPCAV
VGAPLPNTSW AYNDLHPVLN EGRTQILDSG TLVIASVVTG DSGKYSCTRA NSAGATQAEA
YLTVLVRTQI VKPPVDTRVI LGSTAELQCR ISHDPSVPYE VCWFFGEQQL GALSRVRLSP
DGTLRIDQAR NTDIGTYTCM VTSPGGNDTR SARLEVIVAA PLEGERNGRL LGYAVEYRLA
GYPSSPWAGV NVTATRATLE DLIVWQTYAL RVAAFNEKGL GVFSEPIHVR TREGVPQAAP
SGLRADALNS TAVQVRWRPP DPQLVNGLNQ GYRVEAWPRG SAVGVGSPEA SLVVAPLGGA
PLQEHAAVVA GLRKYHSYNL TVLCFTSPGN GPRSAPVLVT TKQDVPGPVG SLKFDDILDV
SVKVLWTPPE DTNGILLGRE GWSGGGKTSA PDARTLSVSP LVPFTEYRLR LLATNVVGPS
PPSEPSQWFQ TIQAPPAHPP RNVTVRAVNA HALRVRWTPL PQVDWYGVPR GYNVSFRTSD
EGDFRWTVVE DHNANSLVLD DLQAFTPYEV FMQAFNDVGT SGPSDTSKER TREAVPSAGP
SQVSAKATSS TTVVVTWGPV PRAHRGGILE GYRVVYRAAK EAEPTRKHIE SNATFTTTLT
ELRKHTSYTV QVLALTRVGD GALSLPPVTV TTFEDVLTPL CLLSQPQSYY AFAVSARTKE
GWGLEARALV LTTASREKPQ APSRPLVSPS QVQARHLTLS WTPGRDGFAP LRCYLLQKIE
AGGPWKELPQ KIDPGATTYT VADLRPATRY LFRLRAVNDL GFSPWSEESN ETWTLPAAPE
VAPTGVVVTP YTTTSITVVW KGIAEEAWNG DLAHPSYRVE ACPVGAGPQE CRSRSLEGAG
GGPLTLEGLQ RDRIYEVRVV ATNGQGDGPT SRPVSVYVGE AVPTGYPRQV RLDAPSPTEV
AVSWAPPPED ERNGELLGYK IFYKAEGDAE EAMEAVPATP AAYTLTDLRR FTRYSVQLLA
FNPAGDGPRS QALQVQTLAD RPGVPGPLDF SDITMNSLNV SWSPPEEPNG VITGYLVNYE
TADLDIESGR QVRQKVSHTF LAVRALCEMT TYRFSVQAET SQGYGPESQR NVTTGPQEGS
PLAPLELALQ RNAGGATLSW KEGPQGSAPI TGYLLEARPS HSGKLFLEYK QRMPFYREPW
FLVVLAAGSM VAIILVVAVL CVKSKTHRYK QEMQQSLQSE DHLSLEDAGF GSPEPSVGAK
RSLTRASLRK PLRSPPRPSP ASVTYSDEDD TKGYDDHCDS SSLTEKPSEM SSSDSQGSES
ESDTKGDPHS FVNHYANVND TLRQSWKRQR VAKPPSYTDS EQDSATAMCL NGGRVVLHNM
AGSRAPLPGF SSFV
//
