ID B7PFS0_IXOSC Unreviewed; 691 AA.
AC B7PFS0;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Cell adhesion molecule, putative {ECO:0000313|EMBL:EEC05442.1, ECO:0000313|EnsemblMetazoa:ISCW017597-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW017597 {ECO:0000313|EMBL:EEC05442.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC05442.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC05442.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW017597-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW017597-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010084317; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010583347; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010586686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010628606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010788280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010923065; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011033676; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011046397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS704057; EEC05442.1; -; Genomic_DNA.
DR RefSeq; XP_002434042.1; XM_002433997.1.
DR AlphaFoldDB; B7PFS0; -.
DR STRING; 6945.B7PFS0; -.
DR PaxDb; 6945-B7PFS0; -.
DR EnsemblMetazoa; ISCW017597-RA; ISCW017597-PA; ISCW017597.
DR KEGG; isc:IscW_ISCW017597; -.
DR VEuPathDB; VectorBase:ISCI017597; -.
DR VEuPathDB; VectorBase:ISCP_018816; -.
DR VEuPathDB; VectorBase:ISCW017597; -.
DR HOGENOM; CLU_001038_1_1_1; -.
DR InParanoid; B7PFS0; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0030424; C:axon; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0098632; F:cell-cell adhesion mediator activity; IBA:GO_Central.
DR GO; GO:0007411; P:axon guidance; IBA:GO_Central.
DR GO; GO:0070593; P:dendrite self-avoidance; IBA:GO_Central.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IBA:GO_Central.
DR CDD; cd00096; Ig; 1.
DR CDD; cd20958; IgI_5_Dscam; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR10075; BASIGIN RELATED; 1.
DR PANTHER; PTHR10075:SF14; DOWN SYNDROME CELL ADHESION MOLECULE 3, ISOFORM E-RELATED; 1.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 4.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 7.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 7.
DR PROSITE; PS50835; IG_LIKE; 7.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 7..88
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 90..177
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 183..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 280..365
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 370..456
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 458..547
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 550..660
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC05442.1"
FT NON_TER 691
FT /evidence="ECO:0000313|EMBL:EEC05442.1"
SQ SEQUENCE 691 AA; 74858 MW; 68EC03C0C08E1A4E CRC64;
PHTQTPPRMA EYRSVVQVEQ GDQAVLPCLA QGNPPPTQTW YRLHGPASSS SSTALVLHGA
RTQDGGKYAC VVNNSAGEDR ADTDLLVTVP LSARLEPLVQ TVDVGRTANL SCRVAGHPVH
GVQWTLNGRP LAKGNPRLTL LSRDLLQVSP VQREDRGMYQ CLAYNQRDSA QGTAQLVIGE
DAPVLEQVFS EQEVRPGTST SLKCSASGNP LPQVTWTLDG APVPEVYHIR IGDYVSNERC
LHVSETSAAA LKLLEGFSFL FLRDSQGGAN FAIYCFLLFP VRPMGNVTAL AGRPVTLHCP
VAGHPIQSIA WLKDGRSLPQ NHRQRTFPNG TLVISDVQRS ADSGWYSCVA QDPDGNSAKG
QLALDVMIPP VVNPFAFPSD LTEGKRAGAA CIVSDGDLPI SVEWRKDGLP LAPALRASVA
EANDYTSFLS FAAVRQSHSG NYTCVASNPA ASANFTAPMV VQVPPRWRQE PRDRAAIMGQ
AVVFDCQAEG FPVPVIRWKK AHGQFGGRDF SVIISNANVQ ILENGSLSIR EADRKDGGQY
MCQAINGVGP GISTVVRLDV HVAAHFERKF QALTVRRGES IALTCRAVGE PPITVTWTRD
RHGFNPTLEP RYVVEEKPGA EGLEYSVHIP TADRRDSSLF SCYAENAYGR DDTNFQVVVQ
EPPDKPRSLE TTSTTSRAAT LVWAPPYSGN S
//
