ID B7PJ87_IXOSC Unreviewed; 253 AA.
AC B7PJ87;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Reductase, putative {ECO:0000313|EMBL:EEC06659.1, ECO:0000313|EnsemblMetazoa:ISCW024221-PA};
GN ORFNames=IscW_ISCW024221 {ECO:0000313|EMBL:EEC06659.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC06659.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC06659.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW024221-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW024221-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
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DR EMBL; ABJB010847895; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS724873; EEC06659.1; -; Genomic_DNA.
DR RefSeq; XP_002407344.1; XM_002407300.1.
DR AlphaFoldDB; B7PJ87; -.
DR STRING; 6945.B7PJ87; -.
DR PaxDb; 6945-B7PJ87; -.
DR EnsemblMetazoa; ISCW024221-RA; ISCW024221-PA; ISCW024221.
DR KEGG; isc:IscW_ISCW024221; -.
DR VEuPathDB; VectorBase:ISCI008706; -.
DR VEuPathDB; VectorBase:ISCP_021627; -.
DR VEuPathDB; VectorBase:ISCW024221; -.
DR HOGENOM; CLU_010194_1_3_1; -.
DR InParanoid; B7PJ87; -.
DR OMA; NCVRPGH; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43639; OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870); 1.
DR PANTHER; PTHR43639:SF1; OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870); 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
SQ SEQUENCE 253 AA; 26792 MW; 9E42A31FB98E7740 CRC64;
MGLASDYPVI LITGGSRGIG AATALLAAQQ GYNVVLSYVA RESDALAVVT AVEAAGRQAL
AVKADCADPE QISRLFEQID QRFGRIDVLV NNAGVLFQQS RLEDLSFERM QRTFAVNTIG
PMLCAQQAAK RMAYCHGGRG GSVVNVSSIA AKLGSPNEYV DYAASKGALE TFTTGFAKEV
AREGVRVNCV RPGHIYTEMH ASGGEPDRVD RLKDSIPMGR GGQAEEVARA ILWLASSEAS
FVTGTFLDAT GGK
//
