ID B7PJV5_IXOSC Unreviewed; 488 AA.
AC B7PJV5;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Endonuclease/exonuclease/phosphatase domain-containing protein {ECO:0000259|Pfam:PF14529};
GN ORFNames=IscW_ISCW004910 {ECO:0000313|EMBL:EEC06877.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC06877.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC06877.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW004910-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW004910-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010874891; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010909474; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS728629; EEC06877.1; -; Genomic_DNA.
DR RefSeq; XP_002408709.1; XM_002408665.1.
DR AlphaFoldDB; B7PJV5; -.
DR PaxDb; 6945-B7PJV5; -.
DR EnsemblMetazoa; ISCW004910-RA; ISCW004910-PA; ISCW004910.
DR KEGG; isc:IscW_ISCW004910; -.
DR VEuPathDB; VectorBase:ISCI004910; -.
DR VEuPathDB; VectorBase:ISCP_003466; -.
DR VEuPathDB; VectorBase:ISCP_023287; -.
DR VEuPathDB; VectorBase:ISCW004910; -.
DR HOGENOM; CLU_559330_0_0_1; -.
DR InParanoid; B7PJV5; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 324..438
FT /note="Endonuclease/exonuclease/phosphatase"
FT /evidence="ECO:0000259|Pfam:PF14529"
FT REGION 32..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 488 AA; 53814 MW; 208FA8F0D4D078DC CRC64;
MEHTFSVLAA IIERNAAFLV ALNQLVAQFM PPPQFDSSPP EQAWQQDPWQ QRKSRRRNAG
SQETEQSTSH GTESTAASRS MEVPLPQEWP LPGATPKKRR RSPLTARDAE GSTPILTPPQ
TVVLRSIGKK EVSAFTGQEI REAVKQAGID NMEGYTVHRN EKANAIAITT RDPLMVEKLL
QVREIQKGEE TLPLQPYKAL AGNHCRGVIY LPGQGNTVTP ESLREDIDCR DHKVAAARPI
GAKGNTILVT FEGRVLPKKV RYMCEVLDVR EYRPRPLVCF RCHGIGHKMD VCPRGSACCG
TCGSEHDDVQ EVVSTQVKLG DTVIDVHNTY IMPSVGANNA DWINRLVEPK RHTILAGDFN
ARRTAWGYPD KNARGKNIKK ACENSNLQLC NNPDTPTRLA QNTNHNDTSP DLAWTSPKLR
IKWQVLQDAM GSDHLPIRTD LLISTLCVQA SEILGAEPEE PVARSSRVLC VSQGKSLVGG
NSDPAGLS
//
