ID B7PKX3_IXOSC Unreviewed; 426 AA.
AC B7PKX3;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Cytochrome oxidase biogenesis protein, putative {ECO:0000313|EMBL:EEC07245.1, ECO:0000313|EnsemblMetazoa:ISCW018956-PA};
GN ORFNames=IscW_ISCW018956 {ECO:0000313|EMBL:EEC07245.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC07245.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC07245.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW018956-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW018956-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC {ECO:0000256|ARBA:ARBA00009877, ECO:0000256|RuleBase:RU003945}.
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DR EMBL; ABJB010036833; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010423236; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010463118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010924036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011005979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011028619; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011079743; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS736644; EEC07245.1; -; Genomic_DNA.
DR RefSeq; XP_002434421.1; XM_002434376.1.
DR AlphaFoldDB; B7PKX3; -.
DR STRING; 6945.B7PKX3; -.
DR PaxDb; 6945-B7PKX3; -.
DR EnsemblMetazoa; ISCW018956-RA; ISCW018956-PA; ISCW018956.
DR KEGG; isc:IscW_ISCW018956; -.
DR VEuPathDB; VectorBase:ISCI018956; -.
DR VEuPathDB; VectorBase:ISCP_025368; -.
DR VEuPathDB; VectorBase:ISCW018956; -.
DR HOGENOM; CLU_029282_3_1_1; -.
DR InParanoid; B7PKX3; -.
DR OMA; WSISNTI; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IBA:GO_Central.
DR GO; GO:0032979; P:protein insertion into mitochondrial inner membrane from matrix; IBA:GO_Central.
DR CDD; cd20069; 5TM_Oxa1-like; 1.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR NCBIfam; TIGR03592; yidC_oxa1_cterm; 1.
DR PANTHER; PTHR12428:SF66; MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PKX3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003945};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 142..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 144..333
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
SQ SEQUENCE 426 AA; 47130 MW; 8142FF5C36A91843 CRC64;
MNLSNQLRYG VEITWTTRSN LCKSFRRQFS RPFSAKSSCR VLVVNPRNGK FSHCCSVGPL
AVQRRWSSGT DPGTASVQAT LVEAVPPVPA APVPAAPVLE VVDPGALVEH GEGTLQSMGL
GGWAPSGMVQ HCLDLLHSST GLPWWATIAL GTVVVKLLVF PAILKGQKNT IHMNNHLPQM
QVLQAKLSEA RSSVFVLDSA RYANELMLFM KEKQINPLKN MIIPMVQAPV FISFFFALRG
MANLPMESFK TGGMLWFTDL TIPDPYCLLP LITIRLSRVV ALGAESGVRA DNLQWTRYVF
RAMPIVIFPF TMNFPAALLC YWATSNMFTL AQVGLLRVGA VREALNMPAL VKHKKSDLVL
SKKSFMEGVK DSFTNARITR ELEDRVRADE MQFKRAGMGP VVKTYPYNPT KQAFAKGAQD
GRKIND
//
