ID B7PLG9_IXOSC Unreviewed; 402 AA.
AC B7PLG9;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=ABC transporter, putative {ECO:0000313|EMBL:EEC07441.1, ECO:0000313|EnsemblMetazoa:ISCW006417-PA};
DE EC=3.6.3.44 {ECO:0000313|EMBL:EEC07441.1};
GN ORFNames=IscW_ISCW006417 {ECO:0000313|EMBL:EEC07441.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC07441.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC07441.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW006417-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW006417-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ABJB010071781; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010414002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS740275; EEC07441.1; -; Genomic_DNA.
DR RefSeq; XP_002434617.1; XM_002434572.1.
DR AlphaFoldDB; B7PLG9; -.
DR STRING; 6945.B7PLG9; -.
DR PaxDb; 6945-B7PLG9; -.
DR EnsemblMetazoa; ISCW006417-RA; ISCW006417-PA; ISCW006417.
DR KEGG; isc:IscW_ISCW006417; -.
DR VEuPathDB; VectorBase:ISCI006417; -.
DR VEuPathDB; VectorBase:ISCP_022988; -.
DR VEuPathDB; VectorBase:ISCW006417; -.
DR HOGENOM; CLU_000604_1_9_1; -.
DR InParanoid; B7PLG9; -.
DR OMA; VVICIST; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03244; ABCC_MRP_domain2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24223; ATP-BINDING CASSETTE SUB-FAMILY C; 1.
DR PANTHER; PTHR24223:SF461; PROTEIN CBG08354; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:EEC07441.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..126
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 163..397
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 402 AA; 43863 MW; 22A5A48F848D7064 CRC64;
MVSLPSFRQV RRLQSVSRSP VLSHFGETIS GALSIRAFGA TEHFVKTLEY LQDNSVNCHI
HAASLDGCRM VLVQLLTSLL SFGAALVTVL VRHSLDPGMV GMVLSYTLQM ADEVSLVGLM
SVMLTASLVA VERVMEYFNL PQEAPWRNAK VQPAADWPTL GEVTFSDYSA AYRNGDKPVL
QNINFKSPGG QKVGVVGRTG AGKSTCALAL FRVVEPKSGS IVVDDVDVTE IGLHDLRLKM
TIIPQDPVLF DGTLRWNLDP FNEHPDEALW KALEQAHLKD FVSSQESGLD CDIAEGGDNL
SAGQRQLVCL ARALLRQSKV LVLDEATSSV DLETERLVKQ TTRAEFQSTT VITIAHKLHT
VMDCDQILVL SAGEIVEQGS PSDLLKIKDG LFFKMARDAG LT
//
