ID B7PM79_IXOSC Unreviewed; 754 AA.
AC B7PM79;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Jumonji domain-containing protein, putative {ECO:0000313|EMBL:EEC07701.1, ECO:0000313|EnsemblMetazoa:ISCW018588-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW018588 {ECO:0000313|EMBL:EEC07701.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC07701.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC07701.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW018588-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW018588-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; ABJB010449294; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011044219; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011099140; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS746366; EEC07701.1; -; Genomic_DNA.
DR RefSeq; XP_002434877.1; XM_002434832.1.
DR AlphaFoldDB; B7PM79; -.
DR STRING; 6945.B7PM79; -.
DR PaxDb; 6945-B7PM79; -.
DR EnsemblMetazoa; ISCW018588-RA; ISCW018588-PA; ISCW018588.
DR KEGG; isc:IscW_ISCW018588; -.
DR VEuPathDB; VectorBase:ISCI018588; -.
DR VEuPathDB; VectorBase:ISCP_037777; -.
DR VEuPathDB; VectorBase:ISCW018588; -.
DR HOGENOM; CLU_004659_0_0_1; -.
DR InParanoid; B7PM79; -.
DR OMA; YQEVWKC; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0000118; C:histone deacetylase complex; IBA:GO_Central.
DR GO; GO:0031490; F:chromatin DNA binding; IBA:GO_Central.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IBA:GO_Central.
DR GO; GO:0003712; F:transcription coregulator activity; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12549:SF11; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLASE 2, ISOFORM A; 1.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR Pfam; PF02373; JmjC; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PM79};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 508..713
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 220..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC07701.1"
SQ SEQUENCE 754 AA; 84447 MW; A70161BE9E94CC89 CRC64;
FSCRLRYGKN GTVLSGGFSE PSDASEDDLK LWLPPLEHTP KDLDVTTAKI ILSHVGDQFC
DLVEQEREAQ SLHMGDDKTV SWKRVVQGVR EMCDVCETTL FNIHWVCHKC GFVVCIDCYK
AKKNGTLKGE LSELSNLGRD EFQWLLCANR QPHEQDKLMM TQIIAGSALW DVGQDLHRIR
HEWNIPAYCG CGTCSLEDDC KKNPSSNGQL MSAVSKCFSS DKEGSTLNGE TARTGKRKKN
PVNGVNNSSS DEVGGSYSSD SGGSPLSVLA DVALNSSGKM EGGGKGAEEE DEKGDDFSTL
RELLIRPTGG NSKKSSVEEV VTTVIAQTVA KKEEEQQLLH FCRRFPNSQA GRDALPVRVC
TLAESSLLYP KVPHSWLCNG KLLVLHEPRN KNNLLVFQEQ WKRGQPVLVT DVCKSLNMSL
WHPDGFCRDF GDIRNDLVNC RTGNILPNQP MRKFWEGFEN FSKRMKDDDG EYMLLKLKDW
PPGDDFSDML PSRFSDLMKV LPLPEYTHRD GVFNLAGRLP ECFVRPDLGP KMYNAYGSAL
YPTKGTTNLH LDVSDAVNVM VARDVGVSMN IFVLLAEALK AIDDGACDSL TRKRVREKNA
KPGALWHIYN ARDADKIRDL LNKVAVERGE KLEPHHDPIH DQSWYLDQEL RERLFREYAV
EGYAIAQCLG EAVFIPAGAP HQVRNLHSCI KVAEDFVSPE NIAHCFSLTN EFRQLSDTHT
NHEDKLQIKN VIYHAVKDAL VILRANSSSN LSKK
//
