ID   B7PNK5_IXOSC            Unreviewed;       796 AA.
AC   B7PNK5;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   08-NOV-2023, entry version 73.
DE   RecName: Full=SMC hinge domain-containing protein {ECO:0000259|Pfam:PF06470};
DE   Flags: Fragment;
GN   ORFNames=IscW_ISCW006402 {ECO:0000313|EMBL:EEC08177.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945;
RN   [1] {ECO:0000313|EMBL:EEC08177.1, ECO:0000313|Proteomes:UP000001555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC08177.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA   Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA   Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA   Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ISCW006402-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW006402-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   EMBL; ABJB010434427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010509602; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010668937; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010789961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010794000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010977653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS753451; EEC08177.1; -; Genomic_DNA.
DR   RefSeq; XP_002435353.1; XM_002435308.1.
DR   AlphaFoldDB; B7PNK5; -.
DR   STRING; 6945.B7PNK5; -.
DR   PaxDb; 6945-B7PNK5; -.
DR   EnsemblMetazoa; ISCW006402-RA; ISCW006402-PA; ISCW006402.
DR   KEGG; isc:IscW_ISCW006402; -.
DR   VEuPathDB; VectorBase:ISCP_006814; -.
DR   VEuPathDB; VectorBase:ISCW006402; -.
DR   HOGENOM; CLU_353242_0_0_1; -.
DR   InParanoid; B7PNK5; -.
DR   OMA; GHEENCK; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   InterPro; IPR038892; SMCHD1.
DR   PANTHER; PTHR22640:SF2; STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR22640; UNCHARACTERIZED; 1.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   SUPFAM; SSF75553; Smc hinge domain; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:B7PNK5};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT   DOMAIN          526..647
FT                   /note="SMC hinge"
FT                   /evidence="ECO:0000259|Pfam:PF06470"
FT   REGION          763..796
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EEC08177.1"
FT   NON_TER         796
FT                   /evidence="ECO:0000313|EMBL:EEC08177.1"
SQ   SEQUENCE   796 AA;  88412 MW;  83A173B6C6E4539A CRC64;
     LLLKDLAELL IISDGLDYGD VVKSLDQSCG FHVTGLKFMD TKLGSKEVCF QWKGLKDYLR
     LHLVPGVPAT LAYVDYNPSE PVTVSPDGKL PRPLVVQLQD ARGNPTNEPN VKVHLGIDEA
     MKATPPQPPV KTDSKGRASF GVLTLSTKSR VTPKPCEFNI CSTNCRGRFT LGTKAAIGRS
     FINGPVLRLH LTCDPEKPVE LNVDFKGKKT FTVAEELPEI AVHVLAEDGN IMCSLRGKEL
     SMKLLRIDCS PKNQKTFTAN PAESTSSGGI YHFRKVKVPE AAGEYNLQFH FNNGKHMISS
     SVSCCATNLH ADLLIEQFRE HTCVVFQISL TVQPDSPVKI APQQDPTIPS VSNQAKTSSR
     NLLKYLKLDL TDRFGNNTAA NLTGTLTLQI ISPDPAVTEI PHFEGNVNSY QVPICKGSAG
     CPDASKQEEM AKLTKKRTEL LKQLQTFEDL FQTTKNIYTE LEAVIRDAQT EESKFRGELR
     RIGFNSNSIR EEQHVGPAIK TCEVQRQALD NKNKRTFMPA AYPEEPDVLG KIGHLAWVEE
     DDVAAVLSWH MRGDIDVVVT NTMEKAKDVY RKTNGKQQVV AVDSIRRRNL PSLLPHMRNK
     SFVPTGNPKF ALDYFMFQKD PEVCRSVFAN FIGDAIVLDT LDDATKYRTE VTKFSACPTL
     LARTGERIAS TGKFGGAQNR APSLAQLQGN VFGEPPVKDV DRIQEQIQLL KKLAVSMKKQ
     KDAKTELDKQ KQKDTTFTLK KKDYEALKKE LAGVEDAIGR MSAYGQEEER RSLLVPDLVR
     NSPRRQGPST PVAKYP
//