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Database: UniProt
Entry: B7PP47_IXOSC
LinkDB: B7PP47_IXOSC
Original site: B7PP47_IXOSC 
ID   B7PP47_IXOSC            Unreviewed;       202 AA.
AC   B7PP47;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   11-DEC-2019, entry version 62.
DE   SubName: Full=CDK2- associated dual specificity phosphatase, putative {ECO:0000313|VectorBase:ISCW006791-PA};
DE   SubName: Full=CDK2-associated dual specificity phosphatase, putative {ECO:0000313|EMBL:EEC08369.1};
DE            EC=3.1.3.16 {ECO:0000313|EMBL:EEC08369.1};
GN   Name=8051878 {ECO:0000313|VectorBase:ISCW006791-PA};
GN   ORFNames=IscW_ISCW006791 {ECO:0000313|EMBL:EEC08369.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945 {ECO:0000313|Proteomes:UP000001555};
RN   [1] {ECO:0000313|EMBL:EEC08369.1, ECO:0000313|Proteomes:UP000001555, ECO:0000313|VectorBase:ISCW006791-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555,
RC   ECO:0000313|VectorBase:ISCW006791-PA}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC08369.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA   Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA   Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA   Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:ISCW006791-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|VectorBase:ISCW006791-PA};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; ABJB010807823; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS755904; EEC08369.1; -; Genomic_DNA.
DR   RefSeq; XP_002435539.1; XM_002435494.1.
DR   EnsemblMetazoa; ISCW006791-RA; ISCW006791-PA; ISCW006791.
DR   GeneID; 8051878; -.
DR   KEGG; isc:IscW_ISCW006791; -.
DR   VectorBase; ISCW006791-RA; ISCW006791-PA; ISCW006791.
DR   eggNOG; KOG1720; Eukaryota.
DR   eggNOG; COG2453; LUCA.
DR   InParanoid; B7PP47; -.
DR   KO; K14167; -.
DR   OMA; ALPGCKY; -.
DR   OrthoDB; 1539111at2759; -.
DR   PhylomeDB; B7PP47; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IBA:GO_Central.
DR   GO; GO:0007050; P:cell cycle arrest; IBA:GO_Central.
DR   GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR   Gene3D; 3.90.190.10; -; 1.
DR   InterPro; IPR008425; CDK_inhib_3.
DR   InterPro; IPR022778; CDKN3.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; TYR_PHOSPHATASE_dom.
DR   Pfam; PF05706; CDKN3; 1.
DR   PIRSF; PIRSF037322; CDKN3; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; SSF52799; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EEC08369.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT   DOMAIN          109..167
FT                   /note="TYR_PHOSPHATASE_2"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   ACT_SITE        132
FT                   /note="Phosphocysteine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037322-1"
SQ   SEQUENCE   202 AA;  22576 MW;  4F59F8EAF398BA49 CRC64;
     MDSSDEEVSG DYLKPATPLK IDWLDLSMFG YPDSVGLSGL PGCKFKDSWR DTAHDLEYLK
     LEDVSDVFVL CTRGELTLYR VPSLLTEYES HGITVHHHPF QDGTAPGIEQ VLNILKEIGK
     VIEQGKRALV HCFGGLGRTG VVAACLLLNL DDGVTPEYVV RKVQELRGTR AIQTVKQYNF
     IHDFRSLRDM YLGDSDSKLA TE
//
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