ID B7PU34_IXOSC Unreviewed; 318 AA.
AC B7PU34;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=P2X purinoceptor,putative {ECO:0000313|EMBL:EEC10106.1, ECO:0000313|EnsemblMetazoa:ISCW019739-PA};
GN ORFNames=IscW_ISCW019739 {ECO:0000313|EMBL:EEC10106.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC10106.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC10106.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW019739-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW019739-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the P2X receptor family.
CC {ECO:0000256|ARBA:ARBA00009848}.
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DR EMBL; ABJB010450074; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010805987; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010810180; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010960358; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010984538; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS790259; EEC10106.1; -; Genomic_DNA.
DR RefSeq; XP_002405370.1; XM_002405326.1.
DR AlphaFoldDB; B7PU34; -.
DR PaxDb; 6945-B7PU34; -.
DR EnsemblMetazoa; ISCW019739-RA; ISCW019739-PA; ISCW019739.
DR KEGG; isc:IscW_ISCW019739; -.
DR VEuPathDB; VectorBase:ISCI019739; -.
DR VEuPathDB; VectorBase:ISCP_031631; -.
DR VEuPathDB; VectorBase:ISCW019739; -.
DR HOGENOM; CLU_875175_0_0_1; -.
DR InParanoid; B7PU34; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015267; F:channel activity; IEA:UniProt.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR Gene3D; 2.60.490.10; atp-gated p2x4 ion channel domain; 1.
DR InterPro; IPR027309; P2X_extracellular_dom_sf.
DR PANTHER; PTHR10125; P2X PURINOCEPTOR; 1.
DR PANTHER; PTHR10125:SF31; P2X RECEPTOR E; 1.
DR Pfam; PF00864; P2X_receptor; 1.
PE 1: Evidence at protein level;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PU34};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 318 AA; 35629 MW; 613C979F046DF65A CRC64;
MGRVICDRVA NELIDIFDKY GIAGKVITDD ATNFAKAFRI YRANEEATDD GSDIQPKELT
ELLDDQDDAM IARQLPPHHR CAIHTLTLVL PTLTMLISKL EYDAMKVLVF CAPLVTTLLN
GIQKSFSHLM NDRQLILAAT IIPRFKPSMM NELIKLMTSR FKSGALWPNS TGPASLTSFL
EYITKWAQNT KNGVGFISKS TAPGFRVTLT KTRQDKTNKA HTFGQLSGET CVMGLGTCLK
DTVSYIFEYD TLKVVHISNK KIGALNRLIQ LGGVIQLLIN WDCNLDFDAK YCIPKYTFSR
LDDPNAVLAK GWNFRQAH
//
