ID B7PU37_IXOSC Unreviewed; 354 AA.
AC B7PU37;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Lipase, putative {ECO:0000313|EMBL:EEC10109.1, ECO:0000313|EnsemblMetazoa:ISCW007757-PA};
DE EC=3.1.1.3 {ECO:0000313|EMBL:EEC10109.1};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW007757 {ECO:0000313|EMBL:EEC10109.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC10109.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC10109.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW007757-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW007757-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
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DR EMBL; ABJB010155379; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010732442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS790317; EEC10109.1; -; Genomic_DNA.
DR RefSeq; XP_002405379.1; XM_002405335.1.
DR AlphaFoldDB; B7PU37; -.
DR STRING; 6945.B7PU37; -.
DR PaxDb; 6945-B7PU37; -.
DR EnsemblMetazoa; ISCW007757-RA; ISCW007757-PA; ISCW007757.
DR KEGG; isc:IscW_ISCW007757; -.
DR VEuPathDB; VectorBase:ISCP_032000; -.
DR VEuPathDB; VectorBase:ISCW007757; -.
DR HOGENOM; CLU_784310_0_0_1; -.
DR InParanoid; B7PU37; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0016298; F:lipase activity; IBA:GO_Central.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:UniProtKB-EC.
DR GO; GO:0016042; P:lipid catabolic process; IBA:GO_Central.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013818; Lipase.
DR InterPro; IPR000734; TAG_lipase.
DR PANTHER; PTHR11610:SF184; LD47264P; 1.
DR PANTHER; PTHR11610; LIPASE; 1.
DR Pfam; PF00151; Lipase; 1.
DR PRINTS; PR00821; TAGLIPASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 1: Evidence at protein level;
KW Hydrolase {ECO:0000313|EMBL:EEC10109.1};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PU37};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 96..233
FT /note="Lipase"
FT /evidence="ECO:0000259|Pfam:PF00151"
FT NON_TER 354
FT /evidence="ECO:0000313|EMBL:EEC10109.1"
SQ SEQUENCE 354 AA; 37920 MW; 2805E0FEC0D2EBD5 CRC64;
MAGMELLNSH GVDGNGIDFA QATDQSDTGS INNRATITVS STASLGLAAH ADTLVRALLQ
HQDRNVLEIL WNVGECQLNG SDFYYCPENS RSSDVRWYQE AASDARLVAR VVARMLNRFV
NNYDYDLTRA HFIGFGLGAH VGGFVADELG YTGNVLGRLT ALDAASPLFE SQGLSRLSPS
SALRVEAVHT GGARPCGLGM AGPLGTLDIY VNGGERQPHC NGDRMCSHLA ALGYYAQSVE
RCLADAVSTP LPGYWTDITG IVNVRSLAAC RRVSVTLHRS WRLYPVWVEG RDGLEGQKDP
VSLEGLASAE GHVGAVQPVQ DPQDAVVLDA GGRPRSESVV AKLDCVRSHS SIIR
//
