ID B7PWE9_IXOSC Unreviewed; 309 AA.
AC B7PWE9;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Sulfotransferase, putative {ECO:0000313|EMBL:EEC10921.1, ECO:0000313|EnsemblMetazoa:ISCW007336-PA};
DE EC=2.8.2.4 {ECO:0000313|EMBL:EEC10921.1};
GN Name=8032363 {ECO:0000313|EnsemblMetazoa:ISCW007336-PA};
GN ORFNames=IscW_ISCW007336 {ECO:0000313|EMBL:EEC10921.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC10921.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC10921.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW007336-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW007336-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771}.
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DR EMBL; ABJB010137192; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010587237; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS807717; EEC10921.1; -; Genomic_DNA.
DR RefSeq; XP_002409742.1; XM_002409698.1.
DR AlphaFoldDB; B7PWE9; -.
DR PaxDb; 6945-B7PWE9; -.
DR EnsemblMetazoa; ISCW007336-RA; ISCW007336-PA; ISCW007336.
DR GeneID; 120837881; -.
DR KEGG; isc:IscW_ISCW007336; -.
DR VEuPathDB; VectorBase:ISCI007336; -.
DR VEuPathDB; VectorBase:ISCP_008523; -.
DR VEuPathDB; VectorBase:ISCW007336; -.
DR HOGENOM; CLU_027239_2_0_1; -.
DR InParanoid; B7PWE9; -.
DR OMA; SHRCYER; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004304; F:estrone sulfotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF334; SULFOTRANSFERASE SSU-1; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EEC10921.1}.
FT DOMAIN 34..233
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 309 AA; 36068 MW; F12D39027944CE0E CRC64;
MSYQLYRDVD GVYIDREFEE KTVRSVLSYE PQQGDIFIVS YPKCGTTWMQ YITYNIFNDG
VRPPSMMDVF RSVPFLEGRG IRDDKDFPRP LAMKTHLPFS KQPYSEGAKY IYVSRNPYDC
CVSFYHFANT IRAQGKTFDE FFESFVRGKV NFGDYFDHLL SWYAHRSDPN VLFMTYEDLK
KDTEFCVLKV ADFIGEEYGR KLRDQPELFE RIVSNVGLES MKGLEKETKE VTQRRVTEPS
TFPEGVRTKT VIFGGPVQKL FSCELVRKGV VGDWKNHFSP LQVERMKGRI ALKTKGSDVM
CLWKDLDLP
//
