ID B7PXI3_IXOSC Unreviewed; 1019 AA.
AC B7PXI3;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 85.
DE RecName: Full=Splicing factor 3B subunit 3 {ECO:0000256|ARBA:ARBA00040929};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW020447 {ECO:0000313|EMBL:EEC11306.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC11306.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC11306.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW020447-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW020447-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RSE1 family.
CC {ECO:0000256|ARBA:ARBA00038266}.
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DR EMBL; ABJB010277437; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010284412; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010351049; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010385280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010705661; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010829880; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010843455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010946095; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011043809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011100643; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS814443; EEC11306.1; -; Genomic_DNA.
DR RefSeq; XP_002400960.1; XM_002400916.1.
DR AlphaFoldDB; B7PXI3; -.
DR STRING; 6945.B7PXI3; -.
DR PaxDb; 6945-B7PXI3; -.
DR EnsemblMetazoa; ISCW020447-RA; ISCW020447-PA; ISCW020447.
DR KEGG; isc:IscW_ISCW020447; -.
DR VEuPathDB; VectorBase:ISCI020447; -.
DR VEuPathDB; VectorBase:ISCP_019960; -.
DR VEuPathDB; VectorBase:ISCW020447; -.
DR HOGENOM; CLU_003246_0_0_1; -.
DR InParanoid; B7PXI3; -.
DR OMA; PRATGHW; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR GO; GO:0030620; F:U2 snRNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR Gene3D; 1.10.150.910; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR004871; Cleavage/polyA-sp_fac_asu_C.
DR InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR PANTHER; PTHR10644:SF1; SPLICING FACTOR 3B SUBUNIT 3; 1.
DR Pfam; PF03178; CPSF_A; 1.
DR Pfam; PF10433; MMS1_N; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PXI3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 12..258
FT /note="Cleavage/polyadenylation specificity factor A
FT subunit N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10433"
FT DOMAIN 283..357
FT /note="Cleavage/polyadenylation specificity factor A
FT subunit N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10433"
FT DOMAIN 427..508
FT /note="Cleavage/polyadenylation specificity factor A
FT subunit N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10433"
FT DOMAIN 657..985
FT /note="Cleavage/polyadenylation specificity factor A
FT subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03178"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC11306.1"
SQ SEQUENCE 1019 AA; 112670 MW; 640538AD823C19F6 CRC64;
EADSDPTGEA AQNTHQTLTF YELDLGLNHV VRKYSEPLEE HGNFLIAVPG GSDGPSGVLI
CSENYITYKN FGDQPDIRCP IPRRRNDLDD PERGMIFVCS ANHKTKSMFF FLAQTEQGDI
FKITLETDED MVTEIKLKYF DTIPVAASMC VLKTGFLFVA AEFGNHCLYQ IARLGEEDEE
PEFSSAIPLE EGDTFFFAPR ALRNLLPVEE LDSLSPAMGC TIADLANEDT PQLYVACGRG
PRSCLRVLRH GLEASVHAEV LLCVLEWLID CDQNVPILAV HWQVYPEGIR HIRADKRVNE
WRTPGKKAIV KCAVNQRQVV IALTGGELVY FEMDPTGQLN EYTDRREMSA DIICMSLASV
PVGEQRSRFL AVGLADNTVR IISLDPSDCL SPLSMQALPA TPESLSIVEM GLAEMDPSSQ
GVLYLNIGLQ VSEMAVSELP GNPNAVWTVK RKADEDFDAY IIVSFVNATL VLSIGETVEE
VTDSGFLGTT PTLSCAQIGD DALVQALAMS SRSWLSYYYQ NRFHLTPLSY ETLEFASGFS
SEQCPEGIVA ISTNTLRILA LEKLGAVFNQ VSTPLEYTPR KFVVNHDTNH LVVVETDHNA
YTEKMKVQRK QQMAEEMVEA AGEGEQELAA EMAAAFLSET LPEAVFGAPK AGSGMWASVI
RVLNPSDGQS LCKVALEQNE AALSVALVRF TSHPDEQFVV VGAAREMQLN PRVCRGGGLL
LTYRLAPNPE EPMAGPTQLE LVHATPVEEA PTALCPFQGR LLAGVGKCLR LYDLGRKKLL
RKCENKYIPN AIVSIQAMGN RVVVSDVQES FFFLRYKRQE NQLVIFADDS VPRWITASCM
LDYETVAGAD KFGNVSIIRL PSSISDDVDE DPTGIKSLWD RGWLGGSSQK ADVISNFHIG
ETVLSLQKAT LIPGGSESLV YVTLSGTVGV LVPFTAHEDH DFFQHLEMHM RYENPPLCGR
DHLSFRSSYF PVKNVIDGDL CEQFNSLDPS KQKSIAEELD RNPSEVSKKL EDIRTRYAF
//
